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Multiple metabolic pathways fuel the truncated tricarboxylic acid cycle of the prostate to sustain constant citrate production and secretion.
Frégeau-Proulx L, Lacouture A, Berthiaume L, Weidmann C, Harvey M, Gonthier K, Pelletier JF, Neveu B, Jobin C, Bastien D, Bergeron A, Fradet Y, Lacombe L, Laverdière I, Atallah C, Pouliot F, Audet-Walsh É. Frégeau-Proulx L, et al. Among authors: bastien d. Mol Metab. 2022 Aug;62:101516. doi: 10.1016/j.molmet.2022.101516. Epub 2022 May 20. Mol Metab. 2022. PMID: 35598879 Free PMC article.
P2X4 receptors influence inflammasome activation after spinal cord injury.
de Rivero Vaccari JP, Bastien D, Yurcisin G, Pineau I, Dietrich WD, De Koninck Y, Keane RW, Lacroix S. de Rivero Vaccari JP, et al. Among authors: bastien d. J Neurosci. 2012 Feb 29;32(9):3058-66. doi: 10.1523/JNEUROSCI.4930-11.2012. J Neurosci. 2012. PMID: 22378878 Free PMC article.
Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Toulouse JL, Yachnin BJ, Ruediger EH, Deon D, Gagnon M, Saint-Jacques K, Ebert MCCJC, Forge D, Bastien D, Colin DY, Vanden Eynde JJ, Marinier A, Berghuis AM, Pelletier JN. Toulouse JL, et al. Among authors: bastien d. ACS Omega. 2019 Jun 10;4(6):10056-10069. doi: 10.1021/acsomega.9b00640. eCollection 2019 Jun 30. ACS Omega. 2019. PMID: 31460098 Free PMC article.
Investigation of Classical Organic and Ionic Liquid Cosolvents for Early-Stage Screening in Fragment-Based Inhibitor Design with Unrelated Bacterial and Human Dihydrofolate Reductases.
Toulouse JL, Abraham SMJ, Kadnikova N, Bastien D, Gauchot V, Schmitzer AR, Pelletier JN. Toulouse JL, et al. Among authors: bastien d. Assay Drug Dev Technol. 2017 May/Jun;15(4):141-153. doi: 10.1089/adt.2016.768. Epub 2017 Apr 20. Assay Drug Dev Technol. 2017. PMID: 28426233
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