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Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
Bos EM, Binda E, Verploegh ISC, Wembacher E, Hoefnagel D, Balvers RK, Korporaal AL, Conidi A, Warnert EAH, Trivieri N, Visioli A, Zaccarini P, Caiola L, van Wijck R, van der Spek P, Huylebroeck D, Leenstra S, Lamfers MLM, Ram Z, Westphal M, Noske D, Legnani F, DiMeco F, Vescovi AL, Dirven CMF. Bos EM, et al. Among authors: korporaal al. Mol Cancer. 2023 Aug 10;22(1):129. doi: 10.1186/s12943-023-01835-6. Mol Cancer. 2023. PMID: 37563568 Free PMC article. Clinical Trial.
A simplified protocol for the generation of cortical brain organoids.
Eigenhuis KN, Somsen HB, van der Kroeg M, Smeenk H, Korporaal AL, Kushner SA, de Vrij FMS, van den Berg DLC. Eigenhuis KN, et al. Among authors: korporaal al. Front Cell Neurosci. 2023 Apr 4;17:1114420. doi: 10.3389/fncel.2023.1114420. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37082206 Free PMC article.
Hemoglobin switching in mice carrying the Klf1Nan variant.
Korporaal A, Gillemans N, Heshusius S, Cantú I, van den Akker E, van Dijk TB, von Lindern M, Philipsen S. Korporaal A, et al. Haematologica. 2021 Feb 1;106(2):464-473. doi: 10.3324/haematol.2019.239830. Haematologica. 2021. PMID: 32467144 Free PMC article.
BMP4 and Temozolomide Synergize in the Majority of Patient-Derived Glioblastoma Cultures.
Verploegh ISC, Conidi A, El Hassnaoui H, Verhoeven FAM, Korporaal AL, Ntafoulis I, van den Hout MCGN, Brouwer RWW, Lamfers MLM, van IJcken WFJ, Huylebroeck D, Leenstra S. Verploegh ISC, et al. Among authors: korporaal al. Int J Mol Sci. 2024 Sep 22;25(18):10176. doi: 10.3390/ijms251810176. Int J Mol Sci. 2024. PMID: 39337661 Free PMC article.
Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation.
Birkhoff JC, Brouwer RWW, Kolovos P, Korporaal AL, Bermejo-Santos A, Boltsis I, Nowosad K, van den Hout MCGN, Grosveld FG, van IJcken WFJ, Huylebroeck D, Conidi A. Birkhoff JC, et al. Among authors: korporaal al. Hum Mol Genet. 2020 Aug 29;29(15):2535-2550. doi: 10.1093/hmg/ddaa141. Hum Mol Genet. 2020. PMID: 32628253 Free PMC article.