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Page 1
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Nat Metab. 2022 May;4(5):524-533. doi: 10.1038/s42255-022-00565-1. Epub 2022 Jun 2.
Nat Metab. 2022.
PMID: 35655024
Free PMC article.
Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.
Kurniawan H, Franchina DG, Guerra L, Bonetti L, -Baguet LS, Grusdat M, Schlicker L, Hunewald O, Dostert C, Merz MP, Binsfeld C, Duncan GS, Farinelle S, Nonnenmacher Y, Haight J, Das Gupta D, Ewen A, Taskesen R, Halder R, Chen Y, Jäger C, Ollert M, Wilmes P, Vasiliou V, Harris IS, Knobbe-Thomsen CB, Turner JD, Mak TW, Lohoff M, Meiser J, Hiller K, Brenner D.
Kurniawan H, et al. Among authors: ewen a.
Cell Metab. 2020 May 5;31(5):920-936.e7. doi: 10.1016/j.cmet.2020.03.004. Epub 2020 Mar 25.
Cell Metab. 2020.
PMID: 32213345
Free PMC article.
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D.
Soriano-Baguet L, et al. Among authors: ewen a.
Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26.
Cell Rep. 2023.
PMID: 36848289
Free article.
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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D.
Bonetti L, et al. Among authors: ewen a.
bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932.
bioRxiv. 2023.
PMID: 37489135
Free PMC article.
Preprint.
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Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells.
Franchina DG, Kurniawan H, Grusdat M, Binsfeld C, Guerra L, Bonetti L, Soriano-Baguet L, Ewen A, Kobayashi T, Farinelle S, Minafra AR, Vandamme N, Carpentier A, Borgmann FK, Jäger C, Chen Y, Kleinewietfeld M, Vasiliou V, Mittelbronn M, Hiller K, Lang PA, Brenner D.
Franchina DG, et al. Among authors: ewen a.
Nat Commun. 2022 Apr 4;13(1):1789. doi: 10.1038/s41467-022-29426-x.
Nat Commun. 2022.
PMID: 35379825
Free PMC article.
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T Cell Immunosenescence after Early Life Adversity: Association with Cytomegalovirus Infection.
Elwenspoek MMC, Sias K, Hengesch X, Schaan VK, Leenen FAD, Adams P, Mériaux SB, Schmitz S, Bonnemberger F, Ewen A, Schächinger H, Vögele C, Muller CP, Turner JD.
Elwenspoek MMC, et al. Among authors: ewen a.
Front Immunol. 2017 Oct 17;8:1263. doi: 10.3389/fimmu.2017.01263. eCollection 2017.
Front Immunol. 2017.
PMID: 29089944
Free PMC article.
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