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Page 1
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Nat Metab. 2022 May;4(5):524-533. doi: 10.1038/s42255-022-00565-1. Epub 2022 Jun 2.
Nat Metab. 2022.
PMID: 35655024
Free PMC article.
Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Soriano-Baguet L, Grusdat M, Kurniawan H, Benzarti M, Binsfeld C, Ewen A, Longworth J, Bonetti L, Guerra L, Franchina DG, Kobayashi T, Horkova V, Verschueren C, Helgueta S, Gérard D, More TH, Henne A, Dostert C, Farinelle S, Lesur A, Gérardy JJ, Jäger C, Mittelbronn M, Sinkkonen L, Hiller K, Meiser J, Brenner D.
Soriano-Baguet L, et al. Among authors: verschueren c.
Cell Rep. 2023 Mar 28;42(3):112153. doi: 10.1016/j.celrep.2023.112153. Epub 2023 Feb 26.
Cell Rep. 2023.
PMID: 36848289
Free article.
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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D.
Bonetti L, et al. Among authors: verschueren c.
bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932.
bioRxiv. 2023.
PMID: 37489135
Free PMC article.
Preprint.
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Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2.
Heinz A, Nonnenmacher Y, Henne A, Khalil MA, Bejkollari K, Dostert C, Hosseini S, Goldmann O, He W, Palorini R, Verschueren C, Korte M, Chiaradonna F, Medina E, Brenner D, Hiller K.
Heinz A, et al. Among authors: verschueren c.
Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166530. doi: 10.1016/j.bbadis.2022.166530. Epub 2022 Aug 28.
Biochim Biophys Acta Mol Basis Dis. 2022.
PMID: 36038039
Free article.
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FHR4-based immunoconjugates direct complement-dependent cytotoxicity and phagocytosis towards HER2-positive cancer cells.
Seguin-Devaux C, Plesseria JM, Verschueren C, Masquelier C, Iserentant G, Fullana M, Józsi M, Cohen JHM, Dervillez X.
Seguin-Devaux C, et al. Among authors: verschueren c.
Mol Oncol. 2019 Dec;13(12):2531-2553. doi: 10.1002/1878-0261.12554. Epub 2019 Sep 30.
Mol Oncol. 2019.
PMID: 31365168
Free PMC article.
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Isolation of an HIV-1 neutralizing peptide mimicking the CXCR4 and CCR5 surface from the heavy-chain complementary determining region 3 repertoire of a viremic controller.
Chevigne A, Delhalle S, Counson M, Beaupain N, Rybicki A, Verschueren C, Staub T, Schmit JC, Seguin-Devaux C, Deroo S.
Chevigne A, et al. Among authors: verschueren c.
AIDS. 2016 Jan 28;30(3):377-82. doi: 10.1097/QAD.0000000000000925.
AIDS. 2016.
PMID: 26760231
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