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Page 1
Transferrin Receptor-Targeted Iduronate-2-sulfatase Penetrates the Blood-Retinal Barrier and Improves Retinopathy in Mucopolysaccharidosis II Mice.
Mol Pharm. 2023 Nov 6;20(11):5901-5909. doi: 10.1021/acs.molpharmaceut.3c00736. Epub 2023 Oct 20.
Mol Pharm. 2023.
PMID: 37860991
Free PMC article.
Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses.
Minami K, Morimoto H, Morioka H, Imakiire A, Kinoshita M, Yamamoto R, Hirato T, Sonoda H.
Minami K, et al. Among authors: imakiire a.
Int J Mol Sci. 2022 Oct 3;23(19):11724. doi: 10.3390/ijms231911724.
Int J Mol Sci. 2022.
PMID: 36233030
Free PMC article.
Review.
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Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice.
Kida S, Koshimura Y, Yoden E, Yoshioka A, Morimoto H, Imakiire A, Tanaka N, Tanaka S, Mori A, Ito J, Inoue A, Yamamoto R, Minami K, Hirato T, Takahashi K, Sonoda H.
Kida S, et al. Among authors: imakiire a.
Mol Ther Methods Clin Dev. 2023 May 12;29:439-449. doi: 10.1016/j.omtm.2023.05.010. eCollection 2023 Jun 8.
Mol Ther Methods Clin Dev. 2023.
PMID: 37251981
Free PMC article.
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Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice.
Morimoto H, Morioka H, Imakiire A, Yamamoto R, Hirato T, Sonoda H, Minami K.
Morimoto H, et al. Among authors: imakiire a.
Mol Ther Methods Clin Dev. 2022 May 10;25:534-544. doi: 10.1016/j.omtm.2022.05.002. eCollection 2022 Jun 9.
Mol Ther Methods Clin Dev. 2022.
PMID: 35662814
Free PMC article.
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Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II.
Yamamoto R, Yoden E, Tanaka N, Kinoshita M, Imakiire A, Hirato T, Minami K.
Yamamoto R, et al. Among authors: imakiire a.
Mol Genet Metab Rep. 2021 Apr 18;27:100758. doi: 10.1016/j.ymgmr.2021.100758. eCollection 2021 Jun.
Mol Genet Metab Rep. 2021.
PMID: 33981582
Free PMC article.
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