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Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation.
Saraswati AP, Relitti N, Brindisi M, Osko JD, Chemi G, Federico S, Grillo A, Brogi S, McCabe NH, Turkington RC, Ibrahim O, O'Sullivan J, Lamponi S, Ghanim M, Kelly VP, Zisterer D, Amet R, Hannon Barroeta P, Vanni F, Ulivieri C, Herp D, Sarno F, Di Costanzo A, Saccoccia F, Ruberti G, Jung M, Altucci L, Gemma S, Butini S, Christianson DW, Campiani G. Saraswati AP, et al. Among authors: hannon barroeta p. ACS Med Chem Lett. 2020 Sep 29;11(11):2268-2276. doi: 10.1021/acsmedchemlett.0c00395. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214839 Free PMC article.
Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers.
McLoughlin EC, Twamley B, O'Brien JE, Hannon Barroeta P, Zisterer DM, Meegan MJ, O'Boyle NM. McLoughlin EC, et al. Among authors: hannon barroeta p. Bioorg Chem. 2023 Dec;141:106877. doi: 10.1016/j.bioorg.2023.106877. Epub 2023 Sep 30. Bioorg Chem. 2023. PMID: 37804699 Free article.