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Page 1
Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores.
Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Elosegui-Artola A, et al. Among authors: beedle aem. Cell. 2017 Nov 30;171(6):1397-1410.e14. doi: 10.1016/j.cell.2017.10.008. Epub 2017 Oct 26. Cell. 2017. PMID: 29107331 Free article.
Mechanical force application to the nucleus regulates nucleocytoplasmic transport.
Andreu I, Granero-Moya I, Chahare NR, Clein K, Molina-Jordán M, Beedle AEM, Elosegui-Artola A, Abenza JF, Rossetti L, Trepat X, Raveh B, Roca-Cusachs P. Andreu I, et al. Among authors: beedle aem. Nat Cell Biol. 2022 Jun;24(6):896-905. doi: 10.1038/s41556-022-00927-7. Epub 2022 Jun 9. Nat Cell Biol. 2022. PMID: 35681009 Free PMC article.
In search of a softer environment.
Beedle AEM, Roca-Cusachs P. Beedle AEM, et al. Nat Mater. 2022 Sep;21(9):995-996. doi: 10.1038/s41563-022-01345-8. Nat Mater. 2022. PMID: 36002724 No abstract available.
The laminin-keratin link shields the nucleus from mechanical deformation and signalling.
Kechagia Z, Sáez P, Gómez-González M, Canales B, Viswanadha S, Zamarbide M, Andreu I, Koorman T, Beedle AEM, Elosegui-Artola A, Derksen PWB, Trepat X, Arroyo M, Roca-Cusachs P. Kechagia Z, et al. Among authors: beedle aem. Nat Mater. 2023 Nov;22(11):1409-1420. doi: 10.1038/s41563-023-01657-3. Epub 2023 Sep 14. Nat Mater. 2023. PMID: 37709930 Free PMC article.
Forcing the reversibility of a mechanochemical reaction.
Beedle AEM, Mora M, Davis CT, Snijders AP, Stirnemann G, Garcia-Manyes S. Beedle AEM, et al. Nat Commun. 2018 Aug 8;9(1):3155. doi: 10.1038/s41467-018-05115-6. Nat Commun. 2018. PMID: 30089863 Free PMC article.
Molecular Fluctuations as a Ruler of Force-Induced Protein Conformations.
Stannard A, Mora M, Beedle AEM, Castro-López M, Board S, Garcia-Manyes S. Stannard A, et al. Among authors: beedle aem. Nano Lett. 2021 Apr 14;21(7):2953-2961. doi: 10.1021/acs.nanolett.1c00051. Epub 2021 Mar 25. Nano Lett. 2021. PMID: 33765390 Free PMC article.
16 results