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Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.
Nat Cancer. 2022 Jul;3(7):852-865. doi: 10.1038/s43018-022-00393-y. Epub 2022 Jun 9.
Nat Cancer. 2022.
PMID: 35681100
Free PMC article.
Development of a novel inducer for EBV lytic therapy.
Tikhmyanova N, Paparoidamis N, Romero-Masters J, Feng X, Mohammed FS, Reddy PAN, Kenney SC, Lieberman PM, Salvino JM.
Tikhmyanova N, et al.
Bioorg Med Chem Lett. 2019 Aug 15;29(16):2259-2264. doi: 10.1016/j.bmcl.2019.06.034. Epub 2019 Jun 22.
Bioorg Med Chem Lett. 2019.
PMID: 31255485
Free PMC article.
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Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo.
Yang Y, Mohammed FS, Zhang N, Sauve AA.
Yang Y, et al.
J Biol Chem. 2019 Jun 7;294(23):9295-9307. doi: 10.1074/jbc.RA118.005772. Epub 2019 Apr 4.
J Biol Chem. 2019.
PMID: 30948509
Free PMC article.
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