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Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.
Vaziri-Gohar A, Cassel J, Mohammed FS, Zarei M, Hue JJ, Hajihassani O, Graor HJ, Srikanth YVV, Karim SA, Abbas A, Prendergast E, Chen V, Katayama ES, Dukleska K, Khokhar I, Andren A, Zhang L, Wu C, Erokwu B, Flask CA, Zarei M, Wang R, Rothermel LD, Romani AMP, Bowers J, Getts R, Tatsuoka C, Morton JP, Bederman I, Brunengraber H, Lyssiotis CA, Salvino JM, Brody JR, Winter JM. Vaziri-Gohar A, et al. Among authors: mohammed fs. Nat Cancer. 2022 Jul;3(7):852-865. doi: 10.1038/s43018-022-00393-y. Epub 2022 Jun 9. Nat Cancer. 2022. PMID: 35681100 Free PMC article.
Development of a novel inducer for EBV lytic therapy.
Tikhmyanova N, Paparoidamis N, Romero-Masters J, Feng X, Mohammed FS, Reddy PAN, Kenney SC, Lieberman PM, Salvino JM. Tikhmyanova N, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2259-2264. doi: 10.1016/j.bmcl.2019.06.034. Epub 2019 Jun 22. Bioorg Med Chem Lett. 2019. PMID: 31255485 Free PMC article.