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Page 1
Sphingolipids in Alzheimer's disease, how can we target them?
Crivelli SM, Giovagnoni C, Visseren L, Scheithauer AL, de Wit N, den Hoedt S, Losen M, Mulder MT, Walter J, de Vries HE, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: den hoedt s. Adv Drug Deliv Rev. 2020;159:214-231. doi: 10.1016/j.addr.2019.12.003. Epub 2020 Jan 3. Adv Drug Deliv Rev. 2020. PMID: 31911096 Review.
SMPD4 regulates mitotic nuclear envelope dynamics and its loss causes microcephaly and diabetes.
Smits DJ, Schot R, Krusy N, Wiegmann K, Utermöhlen O, Mulder MT, den Hoedt S, Yoon G, Deshwar AR, Kresge C, Pletcher B, van Mook M, Ferreira MS, Poot RA, Slotman JA, Kremers GJ, Ahmad A, Albash B, Bastaki L, Marafi D, Dekker J, van Ham TJ, Nguyen L, Mancini GMS. Smits DJ, et al. Among authors: den hoedt s. Brain. 2023 Aug 1;146(8):3528-3541. doi: 10.1093/brain/awad033. Brain. 2023. PMID: 36732302 Free PMC article.
Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of APOE4 Homozygotes and Non-APOE4 Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline.
den Hoedt S, Dorst-Lagerwerf KY, de Vries HE, Rozemuller AJM, Scheltens P, Walter J, Sijbrands EJG, Martinez-Martinez P, Verhoeven AJM, Teunissen CE, Mulder MT. den Hoedt S, et al. J Alzheimers Dis Rep. 2023 May 3;7(1):339-354. doi: 10.3233/ADR220072. eCollection 2023. J Alzheimers Dis Rep. 2023. PMID: 37220621 Free PMC article.
Astrocytic ceramide as possible indicator of neuroinflammation.
de Wit NM, den Hoedt S, Martinez-Martinez P, Rozemuller AJ, Mulder MT, de Vries HE. de Wit NM, et al. Among authors: den hoedt s. J Neuroinflammation. 2019 Feb 25;16(1):48. doi: 10.1186/s12974-019-1436-1. J Neuroinflammation. 2019. PMID: 30803453 Free PMC article.
Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.
de Wit NM, Snkhchyan H, den Hoedt S, Wattimena D, de Vos R, Mulder MT, Walter J, Martinez-Martinez P, Hoozemans JJ, Rozemuller AJ, de Vries HE. de Wit NM, et al. Among authors: den hoedt s. J Alzheimers Dis. 2017;60(3):795-807. doi: 10.3233/JAD-160551. J Alzheimers Dis. 2017. PMID: 27662305
CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, Wouters K, van den Hove DLA, Berkes D, Ledesma MD, Verhaagen J, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: den hoedt s. Alzheimers Res Ther. 2021 Feb 17;13(1):45. doi: 10.1186/s13195-021-00780-0. Alzheimers Res Ther. 2021. PMID: 33597019 Free PMC article.
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4.
Crivelli SM, Luo Q, Kruining DV, Giovagnoni C, Mané-Damas M, den Hoedt S, Berkes D, De Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Wijnands EPM, Bieberich E, Losen M, Martinez-Martinez P. Crivelli SM, et al. Among authors: den hoedt s. Biomed Pharmacother. 2022 Aug;152:113240. doi: 10.1016/j.biopha.2022.113240. Epub 2022 Jun 9. Biomed Pharmacother. 2022. PMID: 35689862 Free article.
13 results