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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1958 1
1961 1
1963 1
1964 1
1965 1
1967 1
1969 3
1970 2
1972 5
1973 2
1974 4
1975 4
1976 1
1977 4
1978 5
1979 6
1980 2
1981 13
1982 15
1983 23
1984 11
1985 21
1986 26
1987 40
1988 29
1989 27
1990 41
1991 56
1992 64
1993 57
1994 60
1995 74
1996 64
1997 70
1998 75
1999 107
2000 128
2001 114
2002 115
2003 127
2004 130
2005 128
2006 115
2007 114
2008 120
2009 138
2010 146
2011 123
2012 122
2013 129
2014 141
2015 182
2016 168
2017 139
2018 178
2019 135
2020 144
2021 133
2022 124
2023 134
2024 56

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3,879 results

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Page 1
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Muhammad Tunio G, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y. Hirota S, et al. Among authors: takeda m. Science. 1998 Jan 23;279(5350):577-80. doi: 10.1126/science.279.5350.577. Science. 1998. PMID: 9438854
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the human digestive tract, but their molecular etiology and cellular origin are unknown. Sequencing of c-kit complementary DNA, which encodes a proto-oncogenic receptor tyrosine kinase (KIT), …
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the human digestive tract, but their molecular etiology an …
ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen.
Najnin RA, Al Mahmud MR, Rahman MM, Takeda S, Sasanuma H, Tanaka H, Murakawa Y, Shimizu N, Akter S, Takagi M, Sunada T, Akamatsu S, He G, Itou J, Toi M, Miyaji M, Tsutsui KM, Keeney S, Yamada S. Najnin RA, et al. Among authors: takeda s. Cell Rep. 2023 Jan 31;42(1):111909. doi: 10.1016/j.celrep.2022.111909. Epub 2022 Dec 30. Cell Rep. 2023. PMID: 36640339 Free PMC article.
CRISPR/Cas9 cleavage at the enhancer also causes c-MYC overexpression, indicating that this DSB causes c-MYC overexpression. Estrogen treatment induced c-Myc protein overexpression in mammary epithelial cells of ATM-deficient mice. ...
CRISPR/Cas9 cleavage at the enhancer also causes c-MYC overexpression, indicating that this DSB causes c-MYC overexpression. E …
Layer-Number-Independent Two-Dimensional Ferromagnetism in Cr3Te4.
Wang Y, Kajihara S, Matsuoka H, Saika BK, Yamagami K, Takeda Y, Wadati H, Ishizaka K, Iwasa Y, Nakano M. Wang Y, et al. Among authors: takeda y. Nano Lett. 2022 Dec 28;22(24):9964-9971. doi: 10.1021/acs.nanolett.2c03532. Epub 2022 Dec 14. Nano Lett. 2022. PMID: 36516275
We fabricated Cr(3)Te(4) thin films by molecular-beam epitaxy and found that Cr(3)Te(4) could host two distinct ferromagnetic phases characterized with different Curie temperatures (T(C)). One is the bulk-like "high-T(C) phase" showing room-temperature ferromagnetis …
We fabricated Cr(3)Te(4) thin films by molecular-beam epitaxy and found that Cr(3)Te(4) could host two distinct ferromagnetic phases charact …
Hyperpolarized (13)C Magnetic Resonance Imaging as a Tool for Imaging Tissue Redox State, Oxidative Stress, Inflammation, and Cellular Metabolism.
Stewart NJ, Sato T, Takeda N, Hirata H, Matsumoto S. Stewart NJ, et al. Among authors: takeda n. Antioxid Redox Signal. 2022 Jan;36(1-3):81-94. doi: 10.1089/ars.2021.0139. Epub 2021 Aug 17. Antioxid Redox Signal. 2022. PMID: 34218688 Free PMC article. Review.
The capability to use endogenous metabolites as (13)C-enriched imaging tracers without structural modification makes HP (13)C MRI a promising tool to evaluate redox state in patients with various diseases. ...Future Directions: Applications of HP (13)C metabo …
The capability to use endogenous metabolites as (13)C-enriched imaging tracers without structural modification makes HP (13)C …
Palladium-catalyzed C-C bond cleavage of N-cyclopropyl acylhydrazones.
Fujioka H, Yasui M, Hamada S, Fukumi K, Takeda N, Kobayashi Y, Furuta T, Ueda M. Fujioka H, et al. Among authors: takeda n. Org Biomol Chem. 2024 Apr 24;22(16):3262-3267. doi: 10.1039/d4ob00349g. Org Biomol Chem. 2024. PMID: 38568183
Despite their utility as directing groups, the C-C bond cleavage of cyclopropanes utilizing hydrazones has not been explored. Herein, Pd-catalyzed C-C bond cleavage reaction of N-cyclopropyl acylhydrazones, followed by cycloisomerization to yield pyraz …
Despite their utility as directing groups, the C-C bond cleavage of cyclopropanes utilizing hydrazones has not been explored. …
Tumor-suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer.
Itakura H, Hata T, Okuzaki D, Takeda K, Iso K, Qian Y, Morimoto Y, Adachi T, Hirose H, Yokoyama Y, Ogino T, Miyoshi N, Takahashi H, Uemura M, Mizushima T, Hinoi T, Mori M, Doki Y, Eguchi H, Yamamoto H. Itakura H, et al. Among authors: takeda k. iScience. 2023 Mar 23;26(4):106478. doi: 10.1016/j.isci.2023.106478. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091240 Free PMC article.
Immunohistochemistry identified downregulation of c-MAF as an early tumorigenesis event in CRC, with low c-MAF expression associated with poor prognosis. Of note, c-MAF expression and p53 protein levels were inversely correlated in CRC samples. c-MAF k …
Immunohistochemistry identified downregulation of c-MAF as an early tumorigenesis event in CRC, with low c-MAF expression asso …
Inhibition of c-MET reverses radiation-induced malignant potential in pancreatic cancer.
Mori S, Akita H, Kobayashi S, Iwagami Y, Yamada D, Tomimaru Y, Noda T, Gotoh K, Takeda Y, Tanemura M, Doki Y, Eguchi H. Mori S, et al. Among authors: takeda y. Cancer Lett. 2021 Aug 1;512:51-59. doi: 10.1016/j.canlet.2021.04.029. Epub 2021 May 12. Cancer Lett. 2021. PMID: 33965452
Pancreatic cancer cells that overexpressed c-met also showed enhanced malignant potential, which was reversed by c-Met inhibition. Additionally, c-Met inhibitor suppressed the metastatic potential in a liver metastasis mouse model using c-met-overexpre …
Pancreatic cancer cells that overexpressed c-met also showed enhanced malignant potential, which was reversed by c-Met inhibit …
beta-Glycosyl Trifluoroborates as Precursors for Direct alpha-C-Glycosylation: Synthesis of 2-Deoxy-alpha-C-glycosides.
Takeda D, Yoritate M, Yasutomi H, Chiba S, Moriyama T, Yokoo A, Usui K, Hirai G. Takeda D, et al. Org Lett. 2021 Mar 5;23(5):1940-1944. doi: 10.1021/acs.orglett.1c00402. Epub 2021 Feb 24. Org Lett. 2021. PMID: 33625241
C-Glycosides are metabolically stable mimics of natural O-glycosides and are expected to be useful tools for investigation of the biological functions of glycans. ...Hydrogenation of the vinyl C-glycosides afforded C-linked 2'-deoxydisaccharide analogues....
C-Glycosides are metabolically stable mimics of natural O-glycosides and are expected to be useful tools for investigation of the bio …
Combined small cell lung carcinoma harboring ALK rearrangement: A case report and literature review.
Niitsu T, Shiroyama T, Miyake K, Noda Y, Kido K, Hara R, Enomoto T, Adachi Y, Amiya S, Suga Y, Fukushima K, Koyama S, Iwahori K, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A. Niitsu T, et al. Among authors: takeda y. Thorac Cancer. 2020 Dec;11(12):3625-3630. doi: 10.1111/1759-7714.13716. Epub 2020 Oct 25. Thorac Cancer. 2020. PMID: 33103386 Free PMC article. Review.
Standard chemotherapy for patients with c-SCLC has not yet been established. Gene mutations such as epidermal growth factor receptor (EGFR) mutations may be detected in patients with c-SCLC. However, little is known about anaplastic lymphoma kinase (ALK) rearrangeme …
Standard chemotherapy for patients with c-SCLC has not yet been established. Gene mutations such as epidermal growth factor receptor …
MSC/ECM Cellular Complexes Induce Periodontal Tissue Regeneration.
Takewaki M, Kajiya M, Takeda K, Sasaki S, Motoike S, Komatsu N, Matsuda S, Ouhara K, Mizuno N, Fujita T, Kurihara H. Takewaki M, et al. Among authors: takeda k. J Dent Res. 2017 Aug;96(9):984-991. doi: 10.1177/0022034517708770. Epub 2017 May 18. J Dent Res. 2017. PMID: 28521114
Immunofluorescence analysis revealed that type I collagen fabricated the form of C-MSCs. OIM markedly elevated calcium deposition in C-MSCs at day 10, suggesting its osteogenic differentiation capacity. Both C-MSCs and C-MSCs cultured with OIM transpla …
Immunofluorescence analysis revealed that type I collagen fabricated the form of C-MSCs. OIM markedly elevated calcium deposition in …
3,879 results