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Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery.
Shekarian T, Zinner CP, Bartoszek EM, Duchemin W, Wachnowicz AT, Hogan S, Etter MM, Flammer J, Paganetti C, Martins TA, Schmassmann P, Zanganeh S, Le Goff F, Muraro MG, Ritz MF, Phillips D, Bhate SS, Barlow GL, Nolan GP, Schürch CM, Hutter G. Shekarian T, et al. Among authors: le goff f. Sci Adv. 2022 Jul;8(26):eabn9440. doi: 10.1126/sciadv.abn9440. Epub 2022 Jul 1. Sci Adv. 2022. PMID: 35776791 Free PMC article.
OECD harmonised template 201: Structuring and reporting mechanistic information to foster the integration of new approach methodologies for hazard and risk assessment of chemicals.
Carnesecchi E, Langezaal I, Browne P, Batista-Leite S, Campia I, Coecke S, Dagallier B, Deceuninck P, Dorne JLC, Tarazona JV, Le Goff F, Leinala E, Morath S, Munn S, Richardson J, Paini A, Wittwehr C. Carnesecchi E, et al. Among authors: le goff f. Regul Toxicol Pharmacol. 2023 Aug;142:105426. doi: 10.1016/j.yrtph.2023.105426. Epub 2023 Jun 3. Regul Toxicol Pharmacol. 2023. PMID: 37277057 Review.
NF-κB drives epithelial-mesenchymal mechanisms of lung fibrosis in a translational lung cell model.
Sieber P, Schäfer A, Lieberherr R, Caimi SL, Lüthi U, Ryge J, Bergmann JH, Le Goff F, Stritt M, Blattmann P, Renault B, Rammelt P, Sempere B, Freti D, Studer R, White ES, Birker-Robaczewska M, Boucher M, Nayler O. Sieber P, et al. Among authors: le goff f. JCI Insight. 2023 Feb 8;8(3):e154719. doi: 10.1172/jci.insight.154719. JCI Insight. 2023. PMID: 36520540 Free PMC article.
Stability of screening compounds in wet DMSO.
Engeloch C, Schopfer U, Muckenschnabel I, Le Goff F, Mees H, Boesch K, Popov M. Engeloch C, et al. Among authors: le goff f. J Biomol Screen. 2008 Dec;13(10):999-1006. doi: 10.1177/1087057108326536. Epub 2008 Nov 21. J Biomol Screen. 2008. PMID: 19029012