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An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression.
Cano-Gamez E, Burnham KL, Goh C, Allcock A, Malick ZH, Overend L, Kwok A, Smith DA, Peters-Sengers H, Antcliffe D; GAinS Investigators; McKechnie S, Scicluna BP, van der Poll T, Gordon AC, Hinds CJ, Davenport EE, Knight JC, Webster N, Galley H, Taylor J, Hall S, Addison J, Roughton S, Tennant H, Guleri A, Waddington N, Arawwawala D, Durcan J, Short A, Swan K, Williams S, Smolen S, Mitchell-Inwang C, Gordon T, Errington E, Templeton M, Venatesh P, Ward G, McCauley M, Baudouin S, Higham C, Soar J, Grier S, Hall E, Brett S, Kitson D, Wilson R, Mountford L, Moreno J, Hall P, Hewlett J, McKechnie S, Garrard C, Millo J, Young D, Hutton P, Parsons P, Smiths A, Faras-Arraya R, Soar J, Raymode P, Thompson J, Bowrey S, Kazembe S, Rich N, Andreou P, Hales D, Roberts E, Fletcher S, Rosbergen M, Glister G, Cuesta JM, Bion J, Millar J, Perry EJ, Willis H, Mitchell N, Ruel S, Carrera R, Wilde J, Nilson A, Lees S, Kapila A, Jacques N, Atkinson J, Brown A, Prowse H, Krige A, Bland M, Bullock L, Harrison D, Mills G, Humphreys J, Armitage K, Laha S, Baldwin J, Walsh A, Doherty N, Drage S, Ortiz-Ruiz de Gordoa L, Lowes S, Higham C, Walsh H, Calder V, Swan C, Payne H, Higgins D, Andrews S, Mapp… See abstract for full author list ➔ Cano-Gamez E, et al. Among authors: peters sengers h. Sci Transl Med. 2022 Nov 2;14(669):eabq4433. doi: 10.1126/scitranslmed.abq4433. Epub 2022 Nov 2. Sci Transl Med. 2022. PMID: 36322631 Free PMC article.
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
van Amstel RBE, Kennedy JN, Scicluna BP, Bos LDJ, Peters-Sengers H, Butler JM, Cano-Gamez E, Knight JC, Vlaar APJ, Cremer OL, Angus DC, van der Poll T, Seymour CW, van Vught LA; MARS Consortium. van Amstel RBE, et al. Among authors: peters sengers h. Intensive Care Med. 2023 Nov;49(11):1360-1369. doi: 10.1007/s00134-023-07239-w. Epub 2023 Oct 18. Intensive Care Med. 2023. PMID: 37851064 Free PMC article.
Deep learning-based classification of kidney transplant pathology: a retrospective, multicentre, proof-of-concept study.
Kers J, Bülow RD, Klinkhammer BM, Breimer GE, Fontana F, Abiola AA, Hofstraat R, Corthals GL, Peters-Sengers H, Djudjaj S, von Stillfried S, Hölscher DL, Pieters TT, van Zuilen AD, Bemelman FJ, Nurmohamed AS, Naesens M, Roelofs JJTH, Florquin S, Floege J, Nguyen TQ, Kather JN, Boor P. Kers J, et al. Among authors: peters sengers h. Lancet Digit Health. 2022 Jan;4(1):e18-e26. doi: 10.1016/S2589-7500(21)00211-9. Epub 2021 Nov 15. Lancet Digit Health. 2022. PMID: 34794930 Free article.
Association between age and the host response in critically ill patients with sepsis.
Michels EHA, Butler JM, Reijnders TDY, Cremer OL, Scicluna BP, Uhel F, Peters-Sengers H, Schultz MJ, Knight JC, van Vught LA, van der Poll T; MARS consortium. Michels EHA, et al. Among authors: peters sengers h. Crit Care. 2022 Dec 13;26(1):385. doi: 10.1186/s13054-022-04266-9. Crit Care. 2022. PMID: 36514130 Free PMC article.
Age-related changes in plasma biomarkers and their association with mortality in COVID-19.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, Chouchane O, van Linge CCA, Schuurman AR, Reijnders TDY, Sulzer TAL, Klarenbeek AM, Douma RA; Amsterdam UMC COVID-19 Biobank Study Group; Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group; van Agtmael M, Algera AG, Appelman B, van Baarle F, Beudel M, Bogaard HJ, Bomers M, Bonta P, Bos L, Botta M, de Brabander J, de Bree G, de Bruin S, Bugiani M, Bulle E, Buis DTP, Chouchane O, Cloherty A, Dijkstra M, Dongelmans DA, Dujardin RWG, Elbers P, Fleuren L, Geerlings S, Geijtenbeek T, Girbes A, Goorhuis B, Grobusch MP, Hagens L, Hamann J, Harris V, Hemke R, Hermans SM, Heunks L, Hollmann M, Horn J, Hovius JW, de Jong HK, de Jong MD, Koning R, Lemkes B, Lim EHT, van Mourik N, Nellen J, Nossent EJ, Olie S, Paulus F, Peters E, Pina-Fuentes DAI, van der Poll T, Preckel B, Prins JM, Raasveld J, Reijnders T, de Rotte MCFJ, Schinkel M, Schultz MJ, Schrauwen FAP, Schuurman A, Schuurmans J, Sigaloff K, Slim MA, Smeele P, Smit M, Stijnis CS, Stilma W, Teunissen C, Thoral P, Tsonas AM, Tuinman PR, van der Valk M, Veelo DP, Volleman C, de Vries H, Vught LA, van Vugt M, Wouters D, Zwinderm… See abstract for full author list ➔ Michels EHA, et al. Among authors: peters sengers h. Eur Respir J. 2023 Jul 7;62(1):2300011. doi: 10.1183/13993003.00011-2023. Print 2023 Jul. Eur Respir J. 2023. PMID: 37080568 Free PMC article.
Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia.
Pereverzeva L, Uhel F, Peters Sengers H, Butler J, van Vught LA, Burnham KL, Davenport EE, Knight JC, Cremer OL, Schultz MJ, Bonten MMJ, Scicluna BP, van der Poll T; MARS consortium. Pereverzeva L, et al. Among authors: peters sengers h. Eur Respir J. 2022 Mar 17;59(3):2101856. doi: 10.1183/13993003.01856-2021. Print 2022 Mar. Eur Respir J. 2022. PMID: 34446464 Free article.
Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium.
Metry EL, Garrelfs SF, Deesker LJ, Acquaviva C, D'Ambrosio V, Bacchetta J, Beck BB, Cochat P, Collard L, Hogan J, Ferraro PM, Franssen CFM, Harambat J, Hulton SA, Lipkin GW, Mandrile G, Martin-Higueras C, Mohebbi N, Moochhala SH, Neuhaus TJ, Prikhodina L, Salido E, Topaloglu R, Oosterveld MJS, Groothoff JW, Peters-Sengers H. Metry EL, et al. Among authors: peters sengers h. Kidney Int Rep. 2023 Aug 4;8(10):2029-2042. doi: 10.1016/j.ekir.2023.07.025. eCollection 2023 Oct. Kidney Int Rep. 2023. PMID: 37849991 Free PMC article.
Plasma protein biomarkers reflective of the host response in patients developing Intensive Care Unit-acquired pneumonia.
van Engelen TSR, Reijnders TDY, Paling FP, Bonten MJM, Timbermont L, Malhotra-Kumar S, Kluytmans JAJW, Peters-Sengers H, van der Poll T; ASPIRE-I. C. U. Study Team. van Engelen TSR, et al. Among authors: peters sengers h. Crit Care. 2023 Jul 6;27(1):269. doi: 10.1186/s13054-023-04536-0. Crit Care. 2023. PMID: 37415223 Free PMC article.
The Plasma Lipidomic Landscape in Patients with Sepsis due to Community-acquired Pneumonia.
Chouchane O, Schuurman AR, Reijnders TDY, Peters-Sengers H, Butler JM, Uhel F, Schultz MJ, Bonten MJ, Cremer OL, Calfee CS, Matthay MA, Langley RJ, Alipanah-Lechner N, Kingsmore SF, Rogers A, van Weeghel M, Vaz FM, van der Poll T. Chouchane O, et al. Among authors: peters sengers h. Am J Respir Crit Care Med. 2024 Apr 15;209(8):973-986. doi: 10.1164/rccm.202308-1321OC. Am J Respir Crit Care Med. 2024. PMID: 38240721
62 results