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Page 1
Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers.
Sci Adv. 2022 Jul 22;8(29):eabm8780. doi: 10.1126/sciadv.abm8780. Epub 2022 Jul 20.
Sci Adv. 2022.
PMID: 35857848
Free PMC article.
PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton.
Britton GJ, Ambler R, Clark DJ, Hill EV, Tunbridge HM, McNally KE, Burton BR, Butterweck P, Sabatos-Peyton C, Hampton-O'Neil LA, Verkade P, Wülfing ChC, Wraith DC.
Britton GJ, et al. Among authors: ambler r.
Elife. 2017 Jan 31;6:e20003. doi: 10.7554/eLife.20003.
Elife. 2017.
PMID: 28112644
Free PMC article.
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Systems Imaging of the Immune Synapse.
Ambler R, Ruan X, Murphy RF, Wülfing C.
Ambler R, et al.
Methods Mol Biol. 2017;1584:409-421. doi: 10.1007/978-1-4939-6881-7_25.
Methods Mol Biol. 2017.
PMID: 28255716
Free PMC article.
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Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization.
Edmunds GL, Wong CCW, Ambler R, Milodowski EJ, Alamir H, Cross SJ, Galea G, Wülfing C, Morgan DJ.
Edmunds GL, et al. Among authors: ambler r.
Commun Biol. 2022 Jan 10;5(1):9. doi: 10.1038/s42003-021-02972-8.
Commun Biol. 2022.
PMID: 35013519
Free PMC article.
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Clinical credibility?
Ambler R.
Ambler R.
RCM Midwives. 2006 Apr;9(4):144-5.
RCM Midwives. 2006.
PMID: 16736791
No abstract available.
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PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor.
Ambler R, Edmunds GL, Tan SL, Cirillo S, Pernes JI, Ruan X, Huete-Carrasco J, Wong CCW, Lu J, Ward J, Toti G, Hedges AJ, Dovedi SJ, Murphy RF, Morgan DJ, Wülfing C.
Ambler R, et al.
Sci Signal. 2020 Sep 15;13(649):eaau4518. doi: 10.1126/scisignal.aau4518.
Sci Signal. 2020.
PMID: 32934075
Free PMC article.
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Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics.
Roybal KT, Buck TE, Ruan X, Cho BH, Clark DJ, Ambler R, Tunbridge HM, Zhang J, Verkade P, Wülfing C, Murphy RF.
Roybal KT, et al. Among authors: ambler r.
Sci Signal. 2016 Apr 19;9(424):rs3. doi: 10.1126/scisignal.aad4149.
Sci Signal. 2016.
PMID: 27095595
Free PMC article.
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