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Page 1
Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial.
Nat Med. 2022 Aug;28(8):1612-1618. doi: 10.1038/s41591-022-01886-0. Epub 2022 Aug 1.
Nat Med. 2022.
PMID: 35915157
Free PMC article.
Clinical Trial.
CYP116B5: a new class VII catalytically self-sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes.
Minerdi D, Sadeghi SJ, Di Nardo G, Rua F, Castrignanò S, Allegra P, Gilardi G.
Minerdi D, et al. Among authors: rua f.
Mol Microbiol. 2015 Feb;95(3):539-54. doi: 10.1111/mmi.12883. Epub 2014 Dec 30.
Mol Microbiol. 2015.
PMID: 25425282
Free article.
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Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs.
Rua F, Sadeghi SJ, Castrignanò S, Di Nardo G, Gilardi G.
Rua F, et al.
J Inorg Biochem. 2012 Dec;117:277-84. doi: 10.1016/j.jinorgbio.2012.05.017. Epub 2012 Jun 7.
J Inorg Biochem. 2012.
PMID: 22819650
Free article.
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Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery.
Rua F, Sadeghi SJ, Castrignanò S, Valetti F, Gilardi G.
Rua F, et al.
Bioelectrochemistry. 2015 Oct;105:110-6. doi: 10.1016/j.bioelechem.2015.03.012. Epub 2015 Jun 12.
Bioelectrochemistry. 2015.
PMID: 26092534
Free article.
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Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates.
Rua F, Di Nardo G, Sadeghi SJ, Gilardi G.
Rua F, et al.
Biotechnol Appl Biochem. 2012 Nov-Dec;59(6):479-89. doi: 10.1002/bab.1051.
Biotechnol Appl Biochem. 2012.
PMID: 23586958
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