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Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.
Swale C, Bellini V, Bowler MW, Flore N, Brenier-Pinchart MP, Cannella D, Belmudes L, Mas C, Couté Y, Laurent F, Scherf A, Bougdour A, Hakimi MA. Swale C, et al. Among authors: bellini v. Sci Transl Med. 2022 Aug 3;14(656):eabn3231. doi: 10.1126/scitranslmed.abn3231. Epub 2022 Aug 3. Sci Transl Med. 2022. PMID: 35921477 Free article.
Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon.
Fox BA, Guevara RB, Rommereim LM, Falla A, Bellini V, Pètre G, Rak C, Cantillana V, Dubremetz JF, Cesbron-Delauw MF, Taylor GA, Mercier C, Bzik DJ. Fox BA, et al. Among authors: bellini v. mBio. 2019 Jul 2;10(4):e00589-19. doi: 10.1128/mBio.00589-19. mBio. 2019. PMID: 31266861 Free PMC article.