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Page 1
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species.
Nat Metab. 2022 Dec;4(12):1792-1811. doi: 10.1038/s42255-022-00706-6. Epub 2022 Dec 19.
Nat Metab. 2022.
PMID: 36536136
Free PMC article.
SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis.
Zaganjor E, Yoon H, Spinelli JB, Nunn ER, Laurent G, Keskinidis P, Sivaloganathan S, Joshi S, Notarangelo G, Mulei S, Chvasta MT, Tucker SA, Kalafut K, van de Ven RAH, Clish CB, Haigis MC.
Zaganjor E, et al. Among authors: kalafut k.
Cell Rep. 2021 Jul 13;36(2):109345. doi: 10.1016/j.celrep.2021.109345.
Cell Rep. 2021.
PMID: 34260923
Free PMC article.
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NQO1 protects obese mice through improvements in glucose and lipid metabolism.
Di Francesco A, Choi Y, Bernier M, Zhang Y, Diaz-Ruiz A, Aon MA, Kalafut K, Ehrlich MR, Murt K, Ali A, Pearson KJ, Levan S, Preston JD, Martin-Montalvo A, Martindale JL, Abdelmohsen K, Michel CR, Willmes DM, Henke C, Navas P, Villalba JM, Siegel D, Gorospe M, Fritz K, Biswal S, Ross D, de Cabo R.
Di Francesco A, et al. Among authors: kalafut k.
NPJ Aging Mech Dis. 2020 Nov 19;6(1):13. doi: 10.1038/s41514-020-00051-6.
NPJ Aging Mech Dis. 2020.
PMID: 33298924
Free PMC article.
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Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.
Byles V, Cormerais Y, Kalafut K, Barrera V, Hughes Hallett JE, Sui SH, Asara JM, Adams CM, Hoxhaj G, Ben-Sahra I, Manning BD.
Byles V, et al. Among authors: kalafut k.
Mol Metab. 2021 Nov;53:101309. doi: 10.1016/j.molmet.2021.101309. Epub 2021 Jul 23.
Mol Metab. 2021.
PMID: 34303878
Free PMC article.
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Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
MacArthur MR, Mitchell SJ, Chadaideh KS, Treviño-Villarreal JH, Jung J, Kalafut KC, Reynolds JS, Mann CG, Trocha KM, Tao M, Aye Cho TZ, Koontanatechanon A, Yeliseyev V, Bry L, Longchamp A, Ozaki CK, Lewis CA, Carmody RN, Mitchell JR.
MacArthur MR, et al. Among authors: kalafut kc.
Cell Rep. 2022 Aug 16;40(7):111187. doi: 10.1016/j.celrep.2022.111187.
Cell Rep. 2022.
PMID: 35977507
Free PMC article.
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Short-Term Ketogenic Diet Induces a Molecular Response That Is Distinct From Dietary Protein Restriction.
Kalafut KC, Mitchell SJ, MacArthur MR, Mitchell JR.
Kalafut KC, et al.
Front Nutr. 2022 Mar 30;9:839341. doi: 10.3389/fnut.2022.839341. eCollection 2022.
Front Nutr. 2022.
PMID: 35433789
Free PMC article.
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Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.
Bernier M, Enamorado IN, Gómez-Cabrera MC, Calvo-Rubio M, González-Reyes JA, Price NL, Cortés-Rodríguez AB, Rodríguez-Aguilera JC, Rodríguez-López S, Mitchell SJ, Murt KN, Kalafut K, Williams KM, Ward CW, Stains JP, Brea-Calvo G, Villalba JM, Cortassa S, Aon MA, de Cabo R.
Bernier M, et al. Among authors: kalafut k.
NPJ Aging. 2022 Jun 27;8(1):8. doi: 10.1038/s41514-022-00089-8.
NPJ Aging. 2022.
PMID: 35927269
Free PMC article.
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