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AKTivation mechanisms.
Curr Opin Struct Biol. 2019 Dec;59:47-53. doi: 10.1016/j.sbi.2019.02.004. Epub 2019 Mar 20.
Curr Opin Struct Biol. 2019.
PMID: 30901610
Free PMC article.
Review.
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications.
Salguero AL, Chen M, Balana AT, Chu N, Jiang H, Palanski BA, Bae H, Wright KM, Nathan S, Zhu H, Gabelli SB, Pratt MR, Cole PA.
Salguero AL, et al.
ACS Chem Biol. 2022 Jan 21;17(1):68-76. doi: 10.1021/acschembio.1c00632. Epub 2021 Dec 23.
ACS Chem Biol. 2022.
PMID: 34941261
Free PMC article.
Item in Clipboard
PH domain-mediated autoinhibition and oncogenic activation of Akt.
Bae H, Viennet T, Park E, Chu N, Salguero A, Eck MJ, Arthanari H, Cole PA.
Bae H, et al. Among authors: salguero a.
Elife. 2022 Aug 15;11:e80148. doi: 10.7554/eLife.80148.
Elife. 2022.
PMID: 35968932
Free PMC article.
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Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA.
Chu N, et al. Among authors: salguero al.
Cell. 2018 Aug 9;174(4):897-907.e14. doi: 10.1016/j.cell.2018.07.003. Epub 2018 Aug 2.
Cell. 2018.
PMID: 30078705
Free PMC article.
Item in Clipboard
The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling.
Chu N, Viennet T, Bae H, Salguero A, Boeszoermenyi A, Arthanari H, Cole PA.
Chu N, et al. Among authors: salguero a.
Elife. 2020 Aug 3;9:e59151. doi: 10.7554/eLife.59151.
Elife. 2020.
PMID: 32744507
Free PMC article.
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Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.
Mahon BP, Lomelino CL, Ladwig J, Rankin GM, Driscoll JM, Salguero AL, Pinard MA, Vullo D, Supuran CT, Poulsen SA, McKenna R.
Mahon BP, et al. Among authors: salguero al.
J Med Chem. 2015 Aug 27;58(16):6630-8. doi: 10.1021/acs.jmedchem.5b00845. Epub 2015 Aug 13.
J Med Chem. 2015.
PMID: 26203869
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Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli.
Mahon BP, Lomelino CL, Salguero AL, Driscoll JM, Pinard MA, McKenna R.
Mahon BP, et al. Among authors: salguero al.
Protein Sci. 2015 Nov;24(11):1800-7. doi: 10.1002/pro.2771. Epub 2015 Sep 15.
Protein Sci. 2015.
PMID: 26266677
Free PMC article.
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