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Page 1
Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.
Cancer Discov. 2022 Nov 2;12(11):2646-2665. doi: 10.1158/2159-8290.CD-22-0010.
Cancer Discov. 2022.
PMID: 35984649
Free PMC article.
Genetics and mechanisms of NT5C2-driven chemotherapy resistance in relapsed ALL.
Dieck CL, Ferrando A.
Dieck CL, et al.
Blood. 2019 May 23;133(21):2263-2268. doi: 10.1182/blood-2019-01-852392. Epub 2019 Mar 25.
Blood. 2019.
PMID: 30910786
Free PMC article.
Review.
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Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia.
Tzoneva G, Dieck CL, Oshima K, Ambesi-Impiombato A, Sánchez-Martín M, Madubata CJ, Khiabanian H, Yu J, Waanders E, Iacobucci I, Sulis ML, Kato M, Koh K, Paganin M, Basso G, Gastier-Foster JM, Loh ML, Kirschner-Schwabe R, Mullighan CG, Rabadan R, Ferrando AA.
Tzoneva G, et al. Among authors: dieck cl.
Nature. 2018 Jan 25;553(7689):511-514. doi: 10.1038/nature25186. Epub 2018 Jan 17.
Nature. 2018.
PMID: 29342136
Free PMC article.
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Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Ambesi-Impiombato A, Sánchez-Martín M, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando AA.
Dieck CL, et al.
Cancer Cell. 2018 Jul 9;34(1):136-147.e6. doi: 10.1016/j.ccell.2018.06.003.
Cancer Cell. 2018.
PMID: 29990496
Free PMC article.
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In vitro modeling of endothelial interaction with macrophages and pericytes demonstrates Notch signaling function in the vascular microenvironment.
Tattersall IW, Du J, Cong Z, Cho BS, Klein AM, Dieck CL, Chaudhri RA, Cuervo H, Herts JH, Kitajewski J.
Tattersall IW, et al. Among authors: dieck cl.
Angiogenesis. 2016 Apr;19(2):201-15. doi: 10.1007/s10456-016-9501-1. Epub 2016 Mar 10.
Angiogenesis. 2016.
PMID: 26965898
Free PMC article.
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