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Page 1
Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease.
Acta Neuropathol Commun. 2019 Nov 6;7(1):169. doi: 10.1186/s40478-019-0795-2.
Acta Neuropathol Commun. 2019.
PMID: 31694701
Free PMC article.
The roles of inflammation and immune mechanisms in Alzheimer's disease.
Van Eldik LJ, Carrillo MC, Cole PE, Feuerbach D, Greenberg BD, Hendrix JA, Kennedy M, Kozauer N, Margolin RA, Molinuevo JL, Mueller R, Ransohoff RM, Wilcock DM, Bain L, Bales K.
Van Eldik LJ, et al. Among authors: margolin ra.
Alzheimers Dement (N Y). 2016 May 30;2(2):99-109. doi: 10.1016/j.trci.2016.05.001. eCollection 2016 Jun.
Alzheimers Dement (N Y). 2016.
PMID: 29067297
Free PMC article.
Review.
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects.
Qiu R, Ahn JE, Alexander R, Brodney MA, He P, Leurent C, Mancuso J, Margolin RA, Tankisheva E, Chen D.
Qiu R, et al. Among authors: margolin ra.
J Alzheimers Dis. 2019;71(2):581-595. doi: 10.3233/JAD-190228.
J Alzheimers Dis. 2019.
PMID: 31424395
Free PMC article.
Clinical Trial.
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The APP intracellular domain promotes LRRK2 expression to enable feed-forward neurodegenerative mechanisms in Parkinson's disease.
Zhang ZW, Tu H, Jiang M, Vanan S, Chia SY, Jang SE, Saw WT, Ong ZW, Ma DR, Zhou ZD, Xu J, Guo KH, Yu WP, Ling SC, Margolin RA, Chain DG, Zeng L, Tan EK.
Zhang ZW, et al. Among authors: margolin ra.
Sci Signal. 2022 Aug 23;15(748):eabk3411. doi: 10.1126/scisignal.abk3411. Epub 2022 Aug 23.
Sci Signal. 2022.
PMID: 35998231
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A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Safety, Pharmacokinetics, and Biomarker Results of Subcutaneous Bapineuzumab in Patients with mild to moderate Alzheimer's disease.
Brody M, Liu E, Di J, Lu M, Margolin RA, Werth JL, Booth K, Shadman A, Brashear HR, Novak G.
Brody M, et al. Among authors: margolin ra.
J Alzheimers Dis. 2016 Oct 18;54(4):1509-1519. doi: 10.3233/JAD-160369.
J Alzheimers Dis. 2016.
PMID: 27589523
Clinical Trial.
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