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DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy.
Brain. 2022 Dec 19;145(12):4368-4384. doi: 10.1093/brain/awac313.
Brain. 2022.
PMID: 36039535
Free PMC article.
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10.
Wauters F, Cornelissen T, Imberechts D, Martin S, Koentjoro B, Sue C, Vangheluwe P, Vandenberghe W.
Wauters F, et al.
Autophagy. 2020 Feb;16(2):203-222. doi: 10.1080/15548627.2019.1603548. Epub 2019 Apr 19.
Autophagy. 2020.
PMID: 30945962
Free PMC article.
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The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy.
Cornelissen T, Haddad D, Wauters F, Van Humbeeck C, Mandemakers W, Koentjoro B, Sue C, Gevaert K, De Strooper B, Verstreken P, Vandenberghe W.
Cornelissen T, et al. Among authors: wauters f.
Hum Mol Genet. 2014 Oct 1;23(19):5227-42. doi: 10.1093/hmg/ddu244. Epub 2014 May 22.
Hum Mol Genet. 2014.
PMID: 24852371
Free PMC article.
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