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Conformational ensemble of the human TRPV3 ion channel.
Zubcevic L, Herzik MA Jr, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY. Zubcevic L, et al. Among authors: hirschi m. Nat Commun. 2018 Nov 14;9(1):4773. doi: 10.1038/s41467-018-07117-w. Nat Commun. 2018. PMID: 30429472 Free PMC article.
Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein autophosphorylation by ARQ 197.
Eathiraj S, Palma R, Volckova E, Hirschi M, France DS, Ashwell MA, Chan TC. Eathiraj S, et al. Among authors: hirschi m. J Biol Chem. 2011 Jun 10;286(23):20666-76. doi: 10.1074/jbc.M110.213801. Epub 2011 Mar 24. J Biol Chem. 2011. PMID: 21454604 Free PMC article.
A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor.
Eathiraj S, Palma R, Hirschi M, Volckova E, Nakuci E, Castro J, Chen CR, Chan TC, France DS, Ashwell MA. Eathiraj S, et al. Among authors: hirschi m. J Biol Chem. 2011 Jun 10;286(23):20677-87. doi: 10.1074/jbc.M110.213736. Epub 2011 Mar 24. J Biol Chem. 2011. PMID: 21454610 Free PMC article.