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p legoux[Author]
(30 results)?
Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab-bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study.
Lancet Oncol. 2023 Dec;24(12):1411-1422. doi: 10.1016/S1470-2045(23)00468-0. Epub 2023 Nov 8.
Lancet Oncol. 2023.
PMID: 37951222
The ABRS-P generalised well on the external validation series (surgical resection series, r=0.60 [95% CI 0.51-0.68], p<0.0001; biopsy series, r=0.53 [0.40-0.63], p<0.0001). In the 122 patients treated with atezolizumab-bevacizumab, those with ABRS-P …
The ABRS-P generalised well on the external validation series (surgical resection series, r=0.60 [95% CI 0.51-0.68], p<0.00 …
Prognostic value of tumor mutational burden in patients with oral cavity squamous cell carcinoma treated with upfront surgery.
Moreira A, Poulet A, Masliah-Planchon J, Lecerf C, Vacher S, Larbi Chérif L, Dupain C, Marret G, Girard E, Syx L, Hoffmann C, Jeannot E, Klijanienko J, Guillou I, Mariani O, Dubray-Vautrin A, Badois N, Lesnik M, Choussy O, Calugaru V, Borcoman E, Baulande S, Legoix P, Albaud B, Servant N, Bieche I, Le Tourneau C, Kamal M.
Moreira A, et al. Among authors: legoix p.
ESMO Open. 2021 Aug;6(4):100178. doi: 10.1016/j.esmoop.2021.100178. Epub 2021 Jun 9.
ESMO Open. 2021.
PMID: 34118772
Free PMC article.
High TMB was associated with prolonged OS (P = 0.01 and P = 0.02, in the highest 10% and 20% TMB values, respectively), but not with DFS. Correlation of TMB with OS remained significant in multivariate analysis (P = 0.01 and P = 0.005 in the highest 10 …
High TMB was associated with prolonged OS (P = 0.01 and P = 0.02, in the highest 10% and 20% TMB values, respectively), but no …
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Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma.
Yakicier MC, Legoix P, Vaury C, Gressin L, Tubacher E, Capron F, Bayer J, Degott C, Balabaud C, Zucman-Rossi J.
Yakicier MC, et al. Among authors: legoix p.
Oncogene. 2001 Aug 23;20(37):5232-8. doi: 10.1038/sj.onc.1204674.
Oncogene. 2001.
PMID: 11526514
Our data revealed a relationship between chromosome 16q homozygous deletions and R249S p53 mutations in tumors where the patient had been exposed to aflatoxin B1 (P=0.002). These results are consistent with a role of aflatoxin B1 in the instability of chromosome 16q at the …
Our data revealed a relationship between chromosome 16q homozygous deletions and R249S p53 mutations in tumors where the patient had been ex …
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Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity.
Legoix P, Bluteau O, Bayer J, Perret C, Balabaud C, Belghiti J, Franco D, Thomas G, Laurent-Puig P, Zucman-Rossi J.
Legoix P, et al.
Oncogene. 1999 Jul 8;18(27):4044-6. doi: 10.1038/sj.onc.1202800.
Oncogene. 1999.
PMID: 10435629
Chromosome 1p, 4q and 16p deletions were significantly associated with the absence of beta catenin mutation (P<0.05). Furthermore the Fractional Allelic Loss was significantly smaller in the beta catenin mutated tumors than in the non-mutated tumors (0.12 versus 022). . …
Chromosome 1p, 4q and 16p deletions were significantly associated with the absence of beta catenin mutation (P<0.05). Furthermore …
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