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2022 5
2023 4
2024 2

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Page 1
Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Zhang H, et al. Among authors: george ss. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637402 Free PMC article.
Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy.
Uribe-Herranz M, Beghi S, Ruella M, Parvathaneni K, Salaris S, Kostopoulos N, George SS, Pierini S, Krimitza E, Costabile F, Ghilardi G, Amelsberg KV, Lee YG, Pajarillo R, Markmann C, McGettigan-Croce B, Agarwal D, Frey N, Lacey SF, Scholler J, Gabunia K, Wu G, Chong E, Porter DL, June CH, Schuster SJ, Bhoj V, Facciabene A. Uribe-Herranz M, et al. Among authors: george ss. Mol Ther. 2023 Mar 1;31(3):686-700. doi: 10.1016/j.ymthe.2023.01.012. Epub 2023 Jan 14. Mol Ther. 2023. PMID: 36641624 Free PMC article.
Control of ribosomal RNA synthesis by hematopoietic transcription factors.
Antony C, George SS, Blum J, Somers P, Thorsheim CL, Wu-Corts DJ, Ai Y, Gao L, Lv K, Tremblay MG, Moss T, Tan K, Wilusz JE, Ganley ARD, Pimkin M, Paralkar VR. Antony C, et al. Among authors: george ss. Mol Cell. 2022 Oct 20;82(20):3826-3839.e9. doi: 10.1016/j.molcel.2022.08.027. Epub 2022 Sep 15. Mol Cell. 2022. PMID: 36113481 Free PMC article.
Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance.
Perales-Linares R, Leli NM, Mohei H, Beghi S, Rivera OD, Kostopoulos N, Giglio A, George SS, Uribe-Herranz M, Costabile F, Pierini S, Pustylnikov S, Skoufos G, Barash Y, Hatzigeorgiou AG, Koumenis C, Maity A, Lotze MT, Facciabene A. Perales-Linares R, et al. Among authors: george ss. Cancer Res. 2023 Nov 1;83(21):3562-3576. doi: 10.1158/0008-5472.CAN-22-2499. Cancer Res. 2023. PMID: 37578274 Free PMC article.
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: george ss. Cell Metab. 2024 May 7;36(5):1164-1167. doi: 10.1016/j.cmet.2024.04.002. Epub 2024 Apr 11. Cell Metab. 2024. PMID: 38604169 No abstract available.
PHF6 suppresses self-renewal of leukemic stem cells in AML.
Jalnapurkar SS, Pawar A, George SS, Antony C, Grana J, Gurbuxani S, Paralkar VR. Jalnapurkar SS, et al. Among authors: george ss. bioRxiv [Preprint]. 2024 Jan 18:2024.01.06.573649. doi: 10.1101/2024.01.06.573649. bioRxiv. 2024. PMID: 38260439 Free PMC article. Preprint.
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.
Lu Z, Bae EA, Verginadis II, Zhang H, Cho C, McBrearty N, George SS, Diehl JA, Koumenis C, Bradley LM, Fuchs SY. Lu Z, et al. Among authors: george ss. Cancer Immunol Immunother. 2023 Apr;72(4):815-826. doi: 10.1007/s00262-022-03286-2. Epub 2022 Sep 5. Cancer Immunol Immunother. 2023. PMID: 36063172 Free PMC article.