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Page 1
Evaluation of the orally bioavailable 4-phenylbutyrate-tethered trichostatin A analogue AR42 in models of spinal muscular atrophy.
Sci Rep. 2023 Jun 26;13(1):10374. doi: 10.1038/s41598-023-37496-0.
Sci Rep. 2023.
PMID: 37365234
Free PMC article.
Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.
Morawe MP, Liao F, Amberg W, van Bergeijk J, Chang R, Gulino M, Hamilton C, Hoft C, Lumpkin C, Mastis B, McGlame E, Nuber J, Plaas C, Ravikumar B, Roy K, Schanzenbächer M, Tierno J, Lakics V, Dellovade T, Townsend M.
Morawe MP, et al. Among authors: lumpkin c.
Eur J Pharmacol. 2022 Nov 5;934:175301. doi: 10.1016/j.ejphar.2022.175301. Epub 2022 Sep 30.
Eur J Pharmacol. 2022.
PMID: 36191631
Free article.
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Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.
Kang SA, O'Neill DJ, Machl AW, Lumpkin CJ, Galda SN, Sengupta S, Mahoney SJ, Howell JJ, Molz L, Hahm S, Vlasuk GP, Saiah E.
Kang SA, et al. Among authors: lumpkin cj.
Cell Chem Biol. 2019 Sep 19;26(9):1203-1213.e13. doi: 10.1016/j.chembiol.2019.05.009. Epub 2019 Jun 20.
Cell Chem Biol. 2019.
PMID: 31231029
Free article.
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Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy.
Butchbach MER, Lumpkin CJ, Harris AW, Saieva L, Edwards JD, Workman E, Simard LR, Pellizzoni L, Burghes AHM.
Butchbach MER, et al. Among authors: lumpkin cj.
Exp Neurol. 2016 May;279:13-26. doi: 10.1016/j.expneurol.2016.02.009. Epub 2016 Feb 15.
Exp Neurol. 2016.
PMID: 26892876
Free PMC article.
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Transcriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cells.
Maeda M, Harris AW, Kingham BF, Lumpkin CJ, Opdenaker LM, McCahan SM, Wang W, Butchbach ME.
Maeda M, et al. Among authors: lumpkin cj.
PLoS One. 2014 Sep 5;9(9):e106818. doi: 10.1371/journal.pone.0106818. eCollection 2014.
PLoS One. 2014.
PMID: 25191843
Free PMC article.
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Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons.
Rossi SL, Lumpkin CJ, Harris AW, Holbrook J, Gentillon C, McCahan SM, Wang W, Butchbach MER.
Rossi SL, et al. Among authors: lumpkin cj.
Biochem Biophys Res Commun. 2016 Oct 14;479(2):319-324. doi: 10.1016/j.bbrc.2016.09.068. Epub 2016 Sep 15.
Biochem Biophys Res Commun. 2016.
PMID: 27641670
Free PMC article.
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Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson's disease pathogenesis.
Lumpkin CJ, Patel H, Potts GK, Chaurasia S, Gibilisco L, Srivastava GP, Lee JY, Brown NJ, Amarante P, Williams JD, Karran E, Townsend M, Woods D, Ravikumar B.
Lumpkin CJ, et al.
Mol Brain. 2024 May 22;17(1):26. doi: 10.1186/s13041-024-01099-1.
Mol Brain. 2024.
PMID: 38778381
Free PMC article.
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