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DUX4 expression activates JNK and p38 MAP kinases in myoblasts.
Brennan CM, Hill AS, St Andre M, Li X, Madeti V, Breitkopf S, Garren S, Xue L, Gilbert T, Hadjipanayis A, Monetti M, Emerson CP, Moccia R, Owens J, Christoforou N. Brennan CM, et al. Among authors: st andre m. Dis Model Mech. 2022 Nov 1;15(11):dmm049516. doi: 10.1242/dmm.049516. Epub 2022 Oct 31. Dis Model Mech. 2022. PMID: 36196640 Free PMC article.
1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators.
Piatnitski Chekler EL, Unwalla R, Khan TA, Tangirala RS, Johnson M, St Andre M, Anderson JT, Kenney T, Chiparri S, McNally C, Kilbourne E, Thompson C, Nagpal S, Weber G, Schelling S, Owens J, Morris CA, Powell D, Verhoest PR, Gilbert AM. Piatnitski Chekler EL, et al. Among authors: st andre m. J Med Chem. 2014 Mar 27;57(6):2462-71. doi: 10.1021/jm401625b. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24527807
A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys.
St Andre M, Johnson M, Bansal PN, Wellen J, Robertson A, Opsahl A, Burch PM, Bialek P, Morris C, Owens J. St Andre M, et al. Skelet Muscle. 2017 Nov 9;7(1):25. doi: 10.1186/s13395-017-0141-y. Skelet Muscle. 2017. PMID: 29121992 Free PMC article.