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Page 1
Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.
Samarin J, Fabrowski P, Kurilov R, Nuskova H, Hummel-Eisenbeiss J, Pink H, Li N, Weru V, Alborzinia H, Yildiz U, Grob L, Taubert M, Czech M, Morgen M, Brandstädter C, Becker K, Mao L, Jayavelu AK, Goncalves A, Uhrig U, Seiler J, Lyu Y, Diederichs S, Klingmüller U, Muckenthaler M, Kopp-Schneider A, Teleman A, Miller AK, Gunkel N. Samarin J, et al. Among authors: uhrig u. Redox Biol. 2023 Jun;62:102639. doi: 10.1016/j.redox.2023.102639. Epub 2023 Feb 23. Redox Biol. 2023. PMID: 36958250 Free PMC article.
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.
Dieter SM, Siegl C, Codó PL, Huerta M, Ostermann-Parucha AL, Schulz E, Zowada MK, Martin S, Laaber K, Nowrouzi A, Blatter M, Kreth S, Westermann F, Benner A, Uhrig U, Putzker K, Lewis J, Haegebarth A, Mumberg D, Holton SJ, Weiske J, Toepper LM, Scheib U, Siemeister G, Ball CR, Kuster B, Stoehr G, Hahne H, Johannes S, Lange M, Herbst F, Glimm H. Dieter SM, et al. Among authors: uhrig u. Cell Rep. 2021 Jul 20;36(3):109394. doi: 10.1016/j.celrep.2021.109394. Cell Rep. 2021. PMID: 34289372 Free article.
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
Steimbach RR, Herbst-Gervasoni CJ, Lechner S, Stewart TM, Klinke G, Ridinger J, Géraldy MNE, Tihanyi G, Foley JR, Uhrig U, Kuster B, Poschet G, Casero RA Jr, Médard G, Oehme I, Christianson DW, Gunkel N, Miller AK. Steimbach RR, et al. Among authors: uhrig u. J Am Chem Soc. 2022 Oct 19;144(41):18861-18875. doi: 10.1021/jacs.2c05030. Epub 2022 Oct 6. J Am Chem Soc. 2022. PMID: 36200994 Free PMC article.
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan S, Schöpe PC, Lewis J, Putzker K, Uhrig U, Specker E, von Kries JP, Lindemann P, Omran A, Sanchez-Ibarra HE, Unger A, Zischinsky ML, Klebl B, Walther W, Nazaré M, Kobelt D, Stein U. Yan S, et al. Among authors: uhrig u. Biomed Pharmacother. 2023 Dec;168:115698. doi: 10.1016/j.biopha.2023.115698. Epub 2023 Oct 21. Biomed Pharmacother. 2023. PMID: 37865992 Free article.
11 results