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TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells.
Sakurai M, Weber P, Wolff G, Wieder A, Szendroedi J, Herzig S, Ekim Üstünel B. Sakurai M, et al. Among authors: wieder a. Biochem Biophys Res Commun. 2022 Aug 27;618:46-53. doi: 10.1016/j.bbrc.2022.05.100. Epub 2022 Jun 9. Biochem Biophys Res Commun. 2022. PMID: 35714570
TSC22D4 interacts with Akt1 to regulate glucose metabolism.
Demir S, Wolff G, Wieder A, Maida A, Bühler L, Brune M, Hautzinger O, Feuchtinger A, Poth T, Szendroedi J, Herzig S, Ekim Üstünel B. Demir S, et al. Among authors: wieder a. Sci Adv. 2022 Oct 21;8(42):eabo5555. doi: 10.1126/sciadv.abo5555. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269831 Free PMC article.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: wieder a. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.