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HIRA loss transforms FH-deficient cells.
Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. Valcarcel-Jimenez L, et al. Among authors: mora a. Sci Adv. 2022 Oct 21;8(42):eabq8297. doi: 10.1126/sciadv.abq8297. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269833 Free PMC article.
FOXA2 controls the anti-oxidant response in FH-deficient cells.
Rogerson C, Sciacovelli M, Maddalena LA, Pouikli A, Segarra-Mondejar M, Valcarcel-Jimenez L, Schmidt C, Yang M, Ivanova E, Kent J, Mora A, Cheeseman D, Carroll JS, Kelsey G, Frezza C. Rogerson C, et al. Among authors: mora a. Cell Rep. 2023 Jul 25;42(7):112751. doi: 10.1016/j.celrep.2023.112751. Epub 2023 Jul 4. Cell Rep. 2023. PMID: 37405921 Free PMC article.
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP).
Foley G, Mora A, Ross CM, Bottoms S, Sützl L, Lamprecht ML, Zaugg J, Essebier A, Balderson B, Newell R, Thomson RES, Kobe B, Barnard RT, Guddat L, Schenk G, Carsten J, Gumulya Y, Rost B, Haltrich D, Sieber V, Gillam EMJ, Bodén M. Foley G, et al. Among authors: mora a. PLoS Comput Biol. 2022 Oct 24;18(10):e1010633. doi: 10.1371/journal.pcbi.1010633. eCollection 2022 Oct. PLoS Comput Biol. 2022. PMID: 36279274 Free PMC article.