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Page 1
Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis.
Abe K, Ikeda M, Ide T, Tadokoro T, Miyamoto HD, Furusawa S, Tsutsui Y, Miyake R, Ishimaru K, Watanabe M, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H. Abe K, et al. Among authors: koumura t. Sci Signal. 2022 Nov;15(758):eabn8017. doi: 10.1126/scisignal.abn8017. Epub 2022 Nov 1. Sci Signal. 2022. PMID: 36318618
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury.
Miyamoto HD, Ikeda M, Ide T, Tadokoro T, Furusawa S, Abe K, Ishimaru K, Enzan N, Sada M, Yamamoto T, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H. Miyamoto HD, et al. Among authors: koumura t. JACC Basic Transl Sci. 2022 Jul 27;7(8):800-819. doi: 10.1016/j.jacbts.2022.03.012. eCollection 2022 Aug. JACC Basic Transl Sci. 2022. PMID: 36061338 Free PMC article.
Deferasirox Targeting Ferroptosis Synergistically Ameliorates Myocardial Ischemia Reperfusion Injury in Conjunction With Cyclosporine A.
Ishimaru K, Ikeda M, Miyamoto HD, Furusawa S, Abe K, Watanabe M, Kanamura T, Fujita S, Nishimura R, Toyohara T, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H, Ide T. Ishimaru K, et al. Among authors: koumura t. J Am Heart Assoc. 2024 Jan 2;13(1):e031219. doi: 10.1161/JAHA.123.031219. Epub 2023 Dec 29. J Am Heart Assoc. 2024. PMID: 38158218 Free PMC article.
17 results