Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria.
Kaczor A, Witek K, Podlewska S, Sinou V, Czekajewska J, Żesławska E, Doroz-Płonka A, Lubelska A, Latacz G, Nitek W, Bischoff M, Alibert S, Pagès JM, Jacob C, Karczewska E, Bolla JM, Handzlik J.
Kaczor A, et al. Among authors: karczewska e.
Int J Mol Sci. 2021 Feb 19;22(4):2062. doi: 10.3390/ijms22042062.
Int J Mol Sci. 2021.
PMID: 33669790
Free PMC article.
Microdilution and real-time efflux (RTE) assays were carried out in strains of K. aerogenes to determine the potential of compounds 7-23 to block the multidrug efflux pump AcrAB-TolC. ...The 4-phenylbenzylidene derivative (15) demonstrated significant MDR-reversal "dual ac …
Microdilution and real-time efflux (RTE) assays were carried out in strains of K. aerogenes to determine the potential of compounds 7 …