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Page 1
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps.
Mol Cell. 2021 Nov 18;81(22):4692-4708.e9. doi: 10.1016/j.molcel.2021.09.005. Epub 2021 Sep 22.
Mol Cell. 2021.
PMID: 34555355
Free PMC article.
Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability.
Gaggioli V, Lo CSY, Reverón-Gómez N, Jasencakova Z, Domenech H, Nguyen H, Sidoli S, Tvardovskiy A, Uruci S, Slotman JA, Chai Y, Gonçalves JGSCS, Manolika EM, Jensen ON, Wheeler D, Sridharan S, Chakrabarty S, Demmers J, Kanaar R, Groth A, Taneja N.
Gaggioli V, et al. Among authors: manolika em.
Nat Cell Biol. 2023 Jul;25(7):1017-1032. doi: 10.1038/s41556-023-01167-z. Epub 2023 Jul 6.
Nat Cell Biol. 2023.
PMID: 37414849
Free PMC article.
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Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51.
Heijink AM, Stok C, Porubsky D, Manolika EM, de Kanter JK, Kok YP, Everts M, de Boer HR, Audrey A, Bakker FJ, Wierenga E, Tijsterman M, Guryev V, Spierings DCJ, Knipscheer P, van Boxtel R, Ray Chaudhuri A, Lansdorp PM, van Vugt MATM.
Heijink AM, et al. Among authors: manolika em.
Nat Commun. 2022 Nov 7;13(1):6722. doi: 10.1038/s41467-022-34519-8.
Nat Commun. 2022.
PMID: 36344511
Free PMC article.
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RIF1 promotes replication fork protection and efficient restart to maintain genome stability.
Mukherjee C, Tripathi V, Manolika EM, Heijink AM, Ricci G, Merzouk S, de Boer HR, Demmers J, van Vugt MATM, Ray Chaudhuri A.
Mukherjee C, et al. Among authors: manolika em.
Nat Commun. 2019 Jul 23;10(1):3287. doi: 10.1038/s41467-019-11246-1.
Nat Commun. 2019.
PMID: 31337767
Free PMC article.
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SMARCAD1-mediated active replication fork stability maintains genome integrity.
Lo CSY, van Toorn M, Gaggioli V, Paes Dias M, Zhu Y, Manolika EM, Zhao W, van der Does M, Mukherjee C, G S C Souto Gonçalves J, van Royen ME, French PJ, Demmers J, Smal I, Lans H, Wheeler D, Jonkers J, Chaudhuri AR, Marteijn JA, Taneja N.
Lo CSY, et al. Among authors: manolika em.
Sci Adv. 2021 May 5;7(19):eabe7804. doi: 10.1126/sciadv.abe7804. Print 2021 May.
Sci Adv. 2021.
PMID: 33952518
Free PMC article.
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