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Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML.
Blood Adv. 2023 May 9;7(9):1858-1870. doi: 10.1182/bloodadvances.2022008806.
Blood Adv. 2023.
PMID: 36477975
Free PMC article.
Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort.
Pasi KJ, Lissitchkov T, Mamonov V, Mant T, Timofeeva M, Bagot C, Chowdary P, Georgiev P, Gercheva-Kyuchukova L, Madigan K, Van Nguyen H, Yu Q, Mei B, Benson CC, Ragni MV.
Pasi KJ, et al. Among authors: madigan k.
J Thromb Haemost. 2021 Jun;19(6):1436-1446. doi: 10.1111/jth.15270. Epub 2021 May 18.
J Thromb Haemost. 2021.
PMID: 33587824
Free PMC article.
Clinical Trial.
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Thrombin generation in plasma of patients with haemophilia A and B with inhibitors: Effects of bypassing agents and antithrombin reduction.
Livnat T, Sehgal A, Qian K, Van Nguyen H, Madigan K, Sorensen B, Kenet G.
Livnat T, et al. Among authors: madigan k.
Blood Cells Mol Dis. 2020 May;82:102416. doi: 10.1016/j.bcmd.2020.102416. Epub 2020 Feb 11.
Blood Cells Mol Dis. 2020.
PMID: 32066048
Free article.
Clinical Trial.
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