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Page 1
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines.
Bioorg Chem. 2021 Nov;116:105315. doi: 10.1016/j.bioorg.2021.105315. Epub 2021 Sep 1.
Bioorg Chem. 2021.
PMID: 34496319
Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing.
Falchetti M, Delgobo M, Zancanaro H, Almeida K, das Neves RN, Dos Santos B, Stefanes NM, Bishop A, Santos-Silva MC, Zanotto-Filho A.
Falchetti M, et al. Among authors: stefanes nm.
Comput Biol Med. 2023 Jan;152:106347. doi: 10.1016/j.compbiomed.2022.106347. Epub 2022 Nov 25.
Comput Biol Med. 2023.
PMID: 36493734
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Synthesis of novel pyrazoline derivatives and the evaluation of death mechanisms involved in their antileukemic activity.
Stefanes NM, Toigo J, Maioral MF, Jacques AV, Chiaradia-Delatorre LD, Perondi DM, Ribeiro AAB, Bigolin Á, Pirath IMS, Duarte BF, Nunes RJ, Santos-Silva MC.
Stefanes NM, et al.
Bioorg Med Chem. 2019 Jan 15;27(2):375-382. doi: 10.1016/j.bmc.2018.12.012. Epub 2018 Dec 7.
Bioorg Med Chem. 2019.
PMID: 30579801
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MICONIDINE acetate, a new selective and cytotoxic compound with synergic potential, induces cell cycle arrest and apoptosis in leukemia cells.
Maioral MF, Stefanes NM, Bigolin Á, Zatelli GA, Philippus AC, de Barcellos Falkenberg M, Santos-Silva MC.
Maioral MF, et al. Among authors: stefanes nm.
Invest New Drugs. 2019 Oct;37(5):912-922. doi: 10.1007/s10637-018-0694-6. Epub 2018 Dec 19.
Invest New Drugs. 2019.
PMID: 30569243
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Cytotoxic effect of a novel naphthylchalcone against multiple cancer cells focusing on hematologic malignancies.
Maioral MF, Bodack CDN, Stefanes NM, Bigolin Á, Mascarello A, Chiaradia-Delatorre LD, Yunes RA, Nunes RJ, Santos-Silva MC.
Maioral MF, et al. Among authors: stefanes nm.
Biochimie. 2017 Sep;140:48-57. doi: 10.1016/j.biochi.2017.06.004. Epub 2017 Jun 10.
Biochimie. 2017.
PMID: 28610775
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