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Page 1
PET Imaging in Preclinical Anti-Aβ Drug Development.
Pharm Res. 2022 Jul;39(7):1481-1496. doi: 10.1007/s11095-022-03277-z. Epub 2022 May 2.
Pharm Res. 2022.
PMID: 35501533
Free PMC article.
Review.
Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody.
Faresjö R, Sehlin D, Syvänen S.
Faresjö R, et al.
Fluids Barriers CNS. 2023 May 11;20(1):34. doi: 10.1186/s12987-023-00435-2.
Fluids Barriers CNS. 2023.
PMID: 37170266
Free PMC article.
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Transferrin Receptor Binding BBB-Shuttle Facilitates Brain Delivery of Anti-Aβ-Affibodies.
Faresjö R, Lindberg H, Ståhl S, Löfblom J, Syvänen S, Sehlin D.
Faresjö R, et al.
Pharm Res. 2022 Jul;39(7):1509-1521. doi: 10.1007/s11095-022-03282-2. Epub 2022 May 10.
Pharm Res. 2022.
PMID: 35538266
Free PMC article.
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Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain.
Syvänen S, Fang XT, Faresjö R, Rokka J, Lannfelt L, Olberg DE, Eriksson J, Sehlin D.
Syvänen S, et al. Among authors: faresjo r.
ACS Chem Neurosci. 2020 Dec 16;11(24):4460-4468. doi: 10.1021/acschemneuro.0c00652. Epub 2020 Nov 25.
ACS Chem Neurosci. 2020.
PMID: 33236886
Free PMC article.
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Introducing or removing heparan sulfate binding sites does not alter brain uptake of the blood-brain barrier shuttle scFv8D3.
de la Rosa A, Metzendorf NG, Morrison JI, Faresjö R, Rofo F, Petrovic A, O'Callaghan P, Syvänen S, Hultqvist G.
de la Rosa A, et al. Among authors: faresjo r.
Sci Rep. 2022 Dec 12;12(1):21479. doi: 10.1038/s41598-022-25965-x.
Sci Rep. 2022.
PMID: 36509864
Free PMC article.
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Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size.
Faresjö R, Bonvicini G, Fang XT, Aguilar X, Sehlin D, Syvänen S.
Faresjö R, et al.
Fluids Barriers CNS. 2021 Jun 2;18(1):26. doi: 10.1186/s12987-021-00257-0.
Fluids Barriers CNS. 2021.
PMID: 34078410
Free PMC article.
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