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Page 1
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer.
Cappellesso F, Orban MP, Shirgaonkar N, Berardi E, Serneels J, Neveu MA, Di Molfetta D, Piccapane F, Caroppo R, Debellis L, Ostyn T, Joudiou N, Mignion L, Richiardone E, Jordan BF, Gallez B, Corbet C, Roskams T, DasGupta R, Tejpar S, Di Matteo M, Taverna D, Reshkin SJ, Topal B, Virga F, Mazzone M. Cappellesso F, et al. Among authors: shirgaonkar n. Nat Cancer. 2022 Dec;3(12):1464-1483. doi: 10.1038/s43018-022-00470-2. Epub 2022 Dec 15. Nat Cancer. 2022. PMID: 36522548 Free PMC article.
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity.
Narmada BC, Khakpoor A, Shirgaonkar N, Narayanan S, Aw PPK, Singh M, Ong KH, Owino CO, Ng JWT, Yew HC, Binte Mohamed Nasir NS, Au VB, Sng R, Kaliaperumal N, Khine HHTW, di Tocco FC, Masayuki O, Naikar S, Ng HX, Chia SL, Seah CXY, Alnawaz MH, Wai CLY, Tay AYL, Mangat KS, Chew V, Yu W, Connolly JE, Periyasamy G, Plissonnier ML, Levrero M, Lim SG, DasGupta R. Narmada BC, et al. Among authors: shirgaonkar n. J Hepatol. 2024 Feb 28:S0168-8278(24)00137-5. doi: 10.1016/j.jhep.2024.02.017. Online ahead of print. J Hepatol. 2024. PMID: 38423478 Free article.
The KdmB-EcoA-RpdA-SntB chromatin complex binds regulatory genes and coordinates fungal development with mycotoxin synthesis.
Karahoda B, Pardeshi L, Ulas M, Dong Z, Shirgaonkar N, Guo S, Wang F, Tan K, Sarikaya-Bayram Ö, Bauer I, Dowling P, Fleming AB, Pfannenstiel BT, Luciano-Rosario D, Berger H, Graessle S, Alhussain MM, Strauss J, Keller NP, Wong KH, Bayram Ö. Karahoda B, et al. Among authors: shirgaonkar n. Nucleic Acids Res. 2022 Sep 23;50(17):9797-9813. doi: 10.1093/nar/gkac744. Nucleic Acids Res. 2022. PMID: 36095118 Free PMC article.
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance.
Scolaro T, Manco M, Pecqueux M, Amorim R, Trotta R, Van Acker HH, Van Haele M, Shirgaonkar N, Naulaerts S, Daniluk J, Prenen F, Varamo C, Ponti D, Doglioni G, Ferreira Campos AM, Fernandez Garcia J, Radenkovic S, Rouhi P, Beatovic A, Wang L, Wang Y, Tzoumpa A, Antoranz A, Sargsian A, Di Matteo M, Berardi E, Goveia J, Ghesquière B, Roskams T, Soenen S, Voets T, Manshian B, Fendt SM, Carmeliet P, Garg AD, DasGupta R, Topal B, Mazzone M. Scolaro T, et al. Among authors: shirgaonkar n. Nat Cancer. 2024 Jun 6. doi: 10.1038/s43018-024-00771-8. Online ahead of print. Nat Cancer. 2024. PMID: 38844817