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2019 2
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2022 4
2023 5
2024 1

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14 results

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Page 1
Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4.
Ashton TD, Dans MG, Favuzza P, Ngo A, Lehane AM, Zhang X, Qiu D, Chandra Maity B, De N, Schindler KA, Yeo T, Park H, Uhlemann AC, Churchyard A, Baum J, Fidock DA, Jarman KE, Lowes KN, Baud D, Brand S, Jackson PF, Cowman AF, Sleebs BE. Ashton TD, et al. Among authors: dans mg. J Med Chem. 2023 Mar 9;66(5):3540-3565. doi: 10.1021/acs.jmedchem.2c02092. Epub 2023 Feb 22. J Med Chem. 2023. PMID: 36812492 Free PMC article.
PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum.
Jonsdottir TK, Elsworth B, Cobbold S, Gabriela M, Ploeger E, Parkyn Schneider M, Charnaud SC, Dans MG, McConville M, Bullen HE, Crabb BS, Gilson PR. Jonsdottir TK, et al. Among authors: dans mg. PLoS Pathog. 2023 Jul 31;19(7):e1011006. doi: 10.1371/journal.ppat.1011006. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37523385 Free PMC article.
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites.
Weiss GE, Ragotte RJ, Quinkert D, Lias AM, Dans MG, Boulet C, Looker O, Ventura OD, Williams BG, Crabb BS, Draper SJ, Gilson PR. Weiss GE, et al. Among authors: dans mg. PLoS Pathog. 2023 Sep 15;19(9):e1011182. doi: 10.1371/journal.ppat.1011182. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37713419 Free PMC article.
7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc1 Complex.
Nguyen W, Dans MG, Currie I, Awalt JK, Bailey BL, Lumb C, Ngo A, Favuzza P, Palandri J, Ramesh S, Penington J, Jarman KE, Mukherjee P, Chakraborty A, Maier AG, van Dooren GG, Papenfuss T, Wittlin S, Churchyard A, Baum J, Winzeler EA, Baud D, Brand S, Jackson PF, Cowman AF, Sleebs BE. Nguyen W, et al. Among authors: dans mg. ACS Infect Dis. 2023 Mar 10;9(3):668-691. doi: 10.1021/acsinfecdis.2c00607. Epub 2023 Feb 28. ACS Infect Dis. 2023. PMID: 36853190 Free PMC article.
The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.
Bullen HE, Sanders PR, Dans MG, Jonsdottir TK, Riglar DT, Looker O, Palmer CS, Kouskousis B, Charnaud SC, Triglia T, Gabriela M, Parkyn Schneider M, Chan JA, de Koning-Ward TF, Baum J, Kazura JW, Beeson JG, Cowman AF, Gilson PR, Crabb BS. Bullen HE, et al. Among authors: dans mg. Mol Microbiol. 2022 May;117(5):1245-1262. doi: 10.1111/mmi.14904. Epub 2022 Apr 25. Mol Microbiol. 2022. PMID: 35403274 Free PMC article.
Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.
Dans MG, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, Geoghegan ND, Dawson AT, Das S, Parkyn Schneider M, Jonsdottir TK, Gabriela M, Gancheva MR, Tonkin CJ, Mollard V, Goodman CD, McFadden GI, Wilson DW, Rogers KL, Barry AE, Crabb BS, de Koning-Ward TF, Sleebs BE, Kursula I, Gilson PR. Dans MG, et al. PLoS Biol. 2023 Apr 13;21(4):e3002066. doi: 10.1371/journal.pbio.3002066. eCollection 2023 Apr. PLoS Biol. 2023. PMID: 37053271 Free PMC article.
14 results