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Page 1
An evolved AAV variant enables efficient genetic engineering of murine T cells.
Cell. 2023 Jan 19;186(2):446-460.e19. doi: 10.1016/j.cell.2022.12.022. Epub 2023 Jan 12.
Cell. 2023.
PMID: 36638795
Free PMC article.
Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target.
Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopmann MR, Temple WC, Izgutdina A, Escobar BP, Gorelik M, Ihling CH, Nix MA, Naik A, Xie WH, Hübner J, Rollins LA, Reid SM, Ramos E, Kasap C, Steri V, Serrano JAC, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Logan AC, Rooney CM, Eyquem J, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP.
Mandal K, et al. Among authors: xie wh.
Nat Cancer. 2023 Nov;4(11):1592-1609. doi: 10.1038/s43018-023-00652-6. Epub 2023 Oct 30.
Nat Cancer. 2023.
PMID: 37904046
Free PMC article.
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Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer.
Loo SY, Toh LP, Xie WH, Pathak E, Tan W, Ma S, Lee MY, Shatishwaran S, Yeo JZZ, Yuan J, Ho YY, Peh EKL, Muniandy M, Torta F, Chan J, Tan TJ, Sim Y, Tan V, Tan B, Madhukumar P, Yong WS, Ong KW, Wong CY, Tan PH, Yap YS, Deng LW, Dent R, Foo R, Wenk MR, Lee SC, Ho YS, Lim EH, Tam WL.
Loo SY, et al.
Sci Adv. 2021 Oct 8;7(41):eabh2443. doi: 10.1126/sciadv.abh2443. Epub 2021 Oct 6.
Sci Adv. 2021.
PMID: 34613780
Free PMC article.
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Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
Zhong FL, Robinson K, Teo DET, Tan KY, Lim C, Harapas CR, Yu CH, Xie WH, Sobota RM, Au VB, Hopkins R, D'Osualdo A, Reed JC, Connolly JE, Masters SL, Reversade B.
Zhong FL, et al. Among authors: xie wh.
J Biol Chem. 2018 Dec 7;293(49):18864-18878. doi: 10.1074/jbc.RA118.004350. Epub 2018 Oct 5.
J Biol Chem. 2018.
PMID: 30291141
Free PMC article.
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A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability.
Chia PH, Zhong FL, Niwa S, Bonnard C, Utami KH, Zeng R, Lee H, Eskin A, Nelson SF, Xie WH, Al-Tawalbeh S, El-Khateeb M, Shboul M, Pouladi MA, Al-Raqad M, Reversade B.
Chia PH, et al. Among authors: xie wh.
Elife. 2018 May 22;7:e32451. doi: 10.7554/eLife.32451.
Elife. 2018.
PMID: 29784083
Free PMC article.
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A FRET-based ratiometric fluorescent probe for nitroxyl detection in living cells.
Zhang H, Liu R, Tan Y, Xie WH, Lei H, Cheung HY, Sun H.
Zhang H, et al.
ACS Appl Mater Interfaces. 2015 Mar 11;7(9):5438-43. doi: 10.1021/am508987v. Epub 2015 Feb 25.
ACS Appl Mater Interfaces. 2015.
PMID: 25658137
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