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IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM.
Zannikou M, Duffy JT, Levine RN, Seblani M, Liu Q, Presser A, Arrieta VA, Chen CJ, Sonabend AM, Horbinski CM, Lee-Chang C, Miska J, Lesniak MS, Gottschalk S, Balyasnikova IV. Zannikou M, et al. Among authors: duffy jt. J Immunother Cancer. 2023 Feb;11(2):e006239. doi: 10.1136/jitc-2022-006239. J Immunother Cancer. 2023. PMID: 36759014 Free PMC article.
Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases.
Fares J, Petrosyan E, Kanojia D, Dmello C, Cordero A, Duffy JT, Yeeravalli R, Sahani MH, Zhang P, Rashidi A, Arrieta VA, Ulasov I, Ahmed AU, Miska J, Balyasnikova IV, James CD, Sonabend AM, Heimberger AB, Lesniak MS. Fares J, et al. Among authors: duffy jt. J Clin Invest. 2023 Dec 15;133(24):e161142. doi: 10.1172/JCI161142. J Clin Invest. 2023. PMID: 37847564 Free PMC article.
Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment.
Petrosyan E, Fares J, Fernandez LG, Yeeravalli R, Dmello C, Duffy JT, Zhang P, Lee-Chang C, Miska J, Ahmed AU, Sonabend AM, Balyasnikova IV, Heimberger AB, Lesniak MS. Petrosyan E, et al. Among authors: duffy jt. Mol Cancer Res. 2023 May 1;21(5):389-396. doi: 10.1158/1541-7786.MCR-22-0920. Mol Cancer Res. 2023. PMID: 36652630 Free PMC article.