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The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy.
Chaudhri A, Bu X, Wang Y, Gomez M, Torchia JA, Hua P, Hung SH, Davies MA, Lizee GA, von Andrian U, Hwu P, Freeman GJ. Chaudhri A, et al. Among authors: lizee ga. Front Immunol. 2023 Sep 13;14:1237715. doi: 10.3389/fimmu.2023.1237715. eCollection 2023. Front Immunol. 2023. PMID: 37771579 Free PMC article.
Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention.
Bolivar AM, Duzagac F, Deng N, Reyes-Uribe L, Chang K, Wu W, Bowen CM, Taggart MW, Thirumurthi S, Lynch PM, You YN, Rodriguez-Pascual J, Lipkin SM, Kopetz S, Scheet P, Lizee GA, Reuben A, Sinha KM, Vilar E. Bolivar AM, et al. Among authors: lizee ga. Gastroenterology. 2024 May;166(5):787-801.e11. doi: 10.1053/j.gastro.2024.01.016. Epub 2024 Jan 18. Gastroenterology. 2024. PMID: 38244726 Free article.
Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy.
Lyons YA, Pradeep S, Wu SY, Haemmerle M, Hansen JM, Wagner MJ, Villar-Prados A, Nagaraja AS, Dood RL, Previs RA, Hu W, Zhao Y, Mak DH, Xiao Z, Melendez BD, Lizee GA, Mercado-Uribe I, Baggerly KA, Hwu P, Liu J, Overwijk WW, Coleman RL, Sood AK. Lyons YA, et al. Among authors: lizee ga. Oncotarget. 2017 Aug 24;8(57):96496-96505. doi: 10.18632/oncotarget.20410. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228548 Free PMC article.
NLRC5/MHC class I transactivator is a target for immune evasion in cancer.
Yoshihama S, Roszik J, Downs I, Meissner TB, Vijayan S, Chapuy B, Sidiq T, Shipp MA, Lizee GA, Kobayashi KS. Yoshihama S, et al. Among authors: lizee ga. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5999-6004. doi: 10.1073/pnas.1602069113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162338 Free PMC article.