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Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.
Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, Mascharak S, De Lay M, Imber B, Park CC, Matsumoto K, Lu K, Bergers G, Sali A, Weiss WA, Aghi MK. Jahangiri A, et al. Among authors: mascharak s. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8685-E8694. doi: 10.1073/pnas.1701821114. Epub 2017 Sep 26. Proc Natl Acad Sci U S A. 2017. PMID: 28973887 Free PMC article.
GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance.
Kuang R, Jahangiri A, Mascharak S, Nguyen A, Chandra A, Flanigan PM, Yagnik G, Wagner JR, De Lay M, Carrera D, Castro BA, Hayes J, Sidorov M, Garcia JLI, Eriksson P, Ronen S, Phillips J, Molinaro A, Koliwad S, Aghi MK. Kuang R, et al. Among authors: mascharak s. JCI Insight. 2017 Jan 26;2(2):e88815. doi: 10.1172/jci.insight.88815. JCI Insight. 2017. PMID: 28138554 Free PMC article.