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Year Number of Results
2011 1
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15 results

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Page 1
Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.
Picon S, Boulahjar R, Hoguet V, Baron M, Duplan I, Vallez E, Hennuyer N, Dumont J, Touche V, Dorchies E, Lasalle M, Descat A, Piveteau C, Biela A, Chaput L, Villoutreix BO, Lipka E, Sevin E, Culot M, Gosselet F, Lestavel S, Roussel P, Deprez-Poulain R, Leroux F, Staels B, Deprez B, Tailleux A, Charton J. Picon S, et al. Among authors: dorchies e. J Med Chem. 2023 Sep 14;66(17):11732-11760. doi: 10.1021/acs.jmedchem.2c01881. Epub 2023 Aug 28. J Med Chem. 2023. PMID: 37639383
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.
Dehondt H, Marino A, Butruille L, Mogilenko DA, Nzoussi Loubota AC, Chávez-Talavera O, Dorchies E, Vallez E, Haas J, Derudas B, Bongiovanni A, Tardivel M, Kuipers F, Lefebvre P, Lestavel S, Tailleux A, Dombrowicz D, Caron S, Staels B. Dehondt H, et al. Among authors: dorchies e. Mol Metab. 2023 Mar;69:101686. doi: 10.1016/j.molmet.2023.101686. Epub 2023 Feb 4. Mol Metab. 2023. PMID: 36746333 Free PMC article.
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα.
Clavreul L, Bernard L, Cotte AK, Hennuyer N, Bourouh C, Devos C, Helleboid A, Haas JT, Verrijken A, Gheeraert C, Derudas B, Guille L, Chevalier J, Eeckhoute J, Vallez E, Dorchies E, Van Gaal L, Lassailly G, Francque S, Staels B, Paumelle R. Clavreul L, et al. Among authors: dorchies e. Metabolism. 2024 Feb;151:155720. doi: 10.1016/j.metabol.2023.155720. Epub 2023 Nov 3. Metabolism. 2024. PMID: 37926201
Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity.
Lancel S, Hesselink MK, Woldt E, Rouillé Y, Dorchies E, Delhaye S, Duhem C, Thorel Q, Mayeuf-Louchart A, Pourcet B, Montel V, Schaart G, Beton N, Picquet F, Briand O, Salles JP, Duez H, Schrauwen P, Bastide B, Bailleul B, Staels B, Sebti Y. Lancel S, et al. Among authors: dorchies e. JCI Insight. 2018 May 3;3(9):e98081. doi: 10.1172/jci.insight.98081. JCI Insight. 2018. PMID: 29720572 Free PMC article.
Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System.
Deckmyn B, Domenger D, Blondel C, Ducastel S, Nicolas E, Dorchies E, Caron E, Charton J, Vallez E, Deprez B, Annicotte JS, Lestavel S, Tailleux A, Magnan C, Staels B, Bantubungi K. Deckmyn B, et al. Among authors: dorchies e. Front Mol Neurosci. 2022 Jan 4;14:808603. doi: 10.3389/fnmol.2021.808603. eCollection 2021. Front Mol Neurosci. 2022. PMID: 35058750 Free PMC article.
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.
Dubois V, Gheeraert C, Vankrunkelsven W, Dubois-Chevalier J, Dehondt H, Bobowski-Gerard M, Vinod M, Zummo FP, Güiza F, Ploton M, Dorchies E, Pineau L, Boulinguiez A, Vallez E, Woitrain E, Baugé E, Lalloyer F, Duhem C, Rabhi N, van Kesteren RE, Chiang CM, Lancel S, Duez H, Annicotte JS, Paumelle R, Vanhorebeek I, Van den Berghe G, Staels B, Lefebvre P, Eeckhoute J. Dubois V, et al. Among authors: dorchies e. Mol Syst Biol. 2020 May;16(5):e9156. doi: 10.15252/msb.20199156. Mol Syst Biol. 2020. PMID: 32407006 Free PMC article.
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R. Deleye Y, et al. Among authors: dorchies e. J Biol Chem. 2020 Dec 11;295(50):17310-17322. doi: 10.1074/jbc.RA120.012543. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037071 Free PMC article.
The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids.
Ducastel S, Touche V, Trabelsi MS, Boulinguiez A, Butruille L, Nawrot M, Peschard S, Chávez-Talavera O, Dorchies E, Vallez E, Annicotte JS, Lancel S, Briand O, Bantubungi K, Caron S, Bindels LB, Delzenne NM, Tailleux A, Staels B, Lestavel S. Ducastel S, et al. Among authors: dorchies e. Sci Rep. 2020 Jan 13;10(1):174. doi: 10.1038/s41598-019-56743-x. Sci Rep. 2020. PMID: 31932631 Free PMC article.
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.
Trabelsi MS, Daoudi M, Prawitt J, Ducastel S, Touche V, Sayin SI, Perino A, Brighton CA, Sebti Y, Kluza J, Briand O, Dehondt H, Vallez E, Dorchies E, Baud G, Spinelli V, Hennuyer N, Caron S, Bantubungi K, Caiazzo R, Reimann F, Marchetti P, Lefebvre P, Bäckhed F, Gribble FM, Schoonjans K, Pattou F, Tailleux A, Staels B, Lestavel S. Trabelsi MS, et al. Among authors: dorchies e. Nat Commun. 2015 Jul 2;6:7629. doi: 10.1038/ncomms8629. Nat Commun. 2015. PMID: 26134028 Free PMC article.
Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance.
Lasalle M, Hoguet V, Hennuyer N, Leroux F, Piveteau C, Belloy L, Lestavel S, Vallez E, Dorchies E, Duplan I, Sevin E, Culot M, Gosselet F, Boulahjar R, Herledan A, Staels B, Deprez B, Tailleux A, Charton J. Lasalle M, et al. Among authors: dorchies e. J Med Chem. 2017 May 25;60(10):4185-4211. doi: 10.1021/acs.jmedchem.6b01873. Epub 2017 May 5. J Med Chem. 2017. PMID: 28414465 Free article.
15 results