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Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death.
Arif W, Mathur B, Saikali MF, Chembazhi UV, Toohill K, Song YJ, Hao Q, Karimi S, Blue SM, Yee BA, Van Nostrand EL, Bangru S, Guzman G, Yeo GW, Prasanth KV, Anakk S, Cummins CL, Kalsotra A. Arif W, et al. Among authors: chembazhi uv. Nat Commun. 2023 Feb 9;14(1):551. doi: 10.1038/s41467-023-35932-3. Nat Commun. 2023. PMID: 36759613 Free PMC article.
An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung.
Jones DL, Morley MP, Li X, Ying Y, Cardenas-Diaz FL, Li S, Zhou S, Schaefer SE, Chembazhi UV, Nottingham A, Lin S, Cantu E, Diamond JM, Basil MC, Vaughan AE, Morrisey EE. Jones DL, et al. Among authors: chembazhi uv. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582147. doi: 10.1101/2024.02.26.582147. bioRxiv. 2024. PMID: 38529490 Free PMC article. Preprint.
SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes.
Peng J, Serrano G, Traniello IM, Calleja-Cervantes ME, Chembazhi UV, Bangru S, Ezponda T, Rodriguez-Madoz JR, Kalsotra A, Prosper F, Ochoa I, Hernaez M. Peng J, et al. Among authors: chembazhi uv. Commun Biol. 2022 Apr 12;5(1):351. doi: 10.1038/s42003-022-03319-7. Commun Biol. 2022. PMID: 35414121 Free PMC article.