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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 3
2005 2
2006 1
2007 1
2008 1
2009 3
2011 2
2012 1
2013 1
2019 1
2023 1
2024 1

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16 results

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Page 1
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Numata M, Haginoya N, Shiroishi M, Hirata T, Sato-Otsubo A, Yoshikawa K, Takata Y, Nagase R, Kashimoto Y, Suzuki M, Schulte N, Polier G, Kurimoto A, Tomoe Y, Toyota A, Yoneyama T, Imai E, Watanabe K, Hamada T, Kanada R, Watanabe J, Kagoshima Y, Tokumaru E, Murata K, Baba T, Shinozaki T, Ohtsuka M, Goto K, Karibe T, Deguchi T, Gocho Y, Yoshida M, Tomizawa D, Kato M, Tsutsumi S, Kitagawa M, Abe Y. Numata M, et al. Among authors: haginoya n. Cancer Cell Int. 2023 Feb 25;23(1):36. doi: 10.1186/s12935-023-02877-y. Cancer Cell Int. 2023. PMID: 36841758 Free PMC article.
Discovery of DF-461, a Potent Squalene Synthase Inhibitor.
Ichikawa M, Ohtsuka M, Ohki H, Ota M, Haginoya N, Itoh M, Shibata Y, Ishigai Y, Terayama K, Kanda A, Sugita K. Ichikawa M, et al. Among authors: haginoya n. ACS Med Chem Lett. 2013 Sep 4;4(10):932-6. doi: 10.1021/ml400151c. eCollection 2013 Oct 10. ACS Med Chem Lett. 2013. PMID: 24900587 Free PMC article.
Discovery of novel tricyclic compounds as squalene synthase inhibitors.
Ichikawa M, Ohtsuka M, Ohki H, Haginoya N, Itoh M, Sugita K, Usui H, Suzuki M, Terayama K, Kanda A. Ichikawa M, et al. Among authors: haginoya n. Bioorg Med Chem. 2012 May 1;20(9):3072-93. doi: 10.1016/j.bmc.2012.02.054. Epub 2012 Mar 8. Bioorg Med Chem. 2012. PMID: 22464687
Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: a novel, potent and orally active direct inhibitor of factor Xa.
Nagata T, Yoshino T, Haginoya N, Yoshikawa K, Nagamochi M, Kobayashi S, Komoriya S, Yokomizo A, Muto R, Yamaguchi M, Osanai K, Suzuki M, Kanno H. Nagata T, et al. Among authors: haginoya n. Bioorg Med Chem. 2009 Feb 1;17(3):1193-206. doi: 10.1016/j.bmc.2008.12.037. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19128974
DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model.
Jimbo T, Hatanaka M, Komatsu T, Taira T, Kumazawa K, Maeda N, Suzuki T, Ota M, Haginoya N, Isoyama T, Fujiwara K. Jimbo T, et al. Among authors: haginoya n. Oncotarget. 2019 Aug 27;10(50):5152-5167. doi: 10.18632/oncotarget.27114. eCollection 2019 Aug 27. Oncotarget. 2019. PMID: 31497246 Free PMC article.
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.
Yoshikawa K, Yokomizo A, Naito H, Haginoya N, Kobayashi S, Yoshino T, Nagata T, Mochizuki A, Osanai K, Watanabe K, Kanno H, Ohta T. Yoshikawa K, et al. Among authors: haginoya n. Bioorg Med Chem. 2009 Dec 15;17(24):8206-20. doi: 10.1016/j.bmc.2009.10.023. Epub 2009 Oct 31. Bioorg Med Chem. 2009. PMID: 19884015
16 results