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Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver.
Sci Rep. 2023 Mar 13;13(1):4138. doi: 10.1038/s41598-023-31087-9.
Sci Rep. 2023.
PMID: 36914879
Free PMC article.
Inhibition of the urea cycle by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin increases serum ammonia levels in mice.
Cholico GN, Fling RR, Sink WJ, Nault R, Zacharewski T.
Cholico GN, et al. Among authors: sink wj.
J Biol Chem. 2024 Jan;300(1):105500. doi: 10.1016/j.jbc.2023.105500. Epub 2023 Nov 25.
J Biol Chem. 2024.
PMID: 38013089
Free PMC article.
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Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β-oxidation-like pathway resulting in acrylyl-CoA conjugate buildup.
Orlowska K, Fling RR, Nault R, Sink WJ, Schilmiller AL, Zacharewski T.
Orlowska K, et al. Among authors: sink wj.
J Biol Chem. 2022 Sep;298(9):102301. doi: 10.1016/j.jbc.2022.102301. Epub 2022 Aug 2.
J Biol Chem. 2022.
PMID: 35931118
Free PMC article.
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