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Page 1
Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation.
Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1;323(5):L536-L547. doi: 10.1152/ajplung.00454.2021. Epub 2022 Sep 13.
Am J Physiol Lung Cell Mol Physiol. 2022.
PMID: 36098422
Free PMC article.
Potential strategies for increasing drug-discovery productivity.
Cumming JG, Finlay MR, Giordanetto F, Hemmerling M, Lister T, Sanganee H, Waring MJ.
Cumming JG, et al. Among authors: hemmerling m.
Future Med Chem. 2014 Apr;6(5):515-27. doi: 10.4155/fmc.14.7.
Future Med Chem. 2014.
PMID: 24649955
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Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA.
Joubert F, Munson MJ, Sabirsh A, England RM, Hemmerling M, Alexander C, Ashford MB.
Joubert F, et al. Among authors: hemmerling m.
J Control Release. 2023 Apr;356:580-594. doi: 10.1016/j.jconrel.2023.03.011. Epub 2023 Mar 17.
J Control Release. 2023.
PMID: 36918085
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Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
Hemmerling M, Nilsson S, Edman K, Eirefelt S, Russell W, Hendrickx R, Johnsson E, Kärrman Mårdh C, Berger M, Rehwinkel H, Abrahamsson A, Dahmén J, Eriksson AR, Gabos B, Henriksson K, Hossain N, Ivanova S, Jansson AH, Jensen TJ, Jerre A, Johansson H, Klingstedt T, Lepistö M, Lindsjö M, Mile I, Nikitidis G, Steele J, Tehler U, Wissler L, Hansson T.
Hemmerling M, et al.
J Med Chem. 2017 Oct 26;60(20):8591-8605. doi: 10.1021/acs.jmedchem.7b01215. Epub 2017 Oct 12.
J Med Chem. 2017.
PMID: 28937774
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Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators.
Hemmerling M, Edman K, Lepistö M, Eriksson A, Ivanova S, Dahmén J, Rehwinkel H, Berger M, Hendrickx R, Dearman M, Jensen TJ, Wissler L, Hansson T.
Hemmerling M, et al.
Bioorg Med Chem Lett. 2016 Dec 1;26(23):5741-5748. doi: 10.1016/j.bmcl.2016.10.052. Epub 2016 Oct 19.
Bioorg Med Chem Lett. 2016.
PMID: 27810243
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Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition.
Åstrand AB, Hemmerling M, Root J, Wingren C, Pesic J, Johansson E, Garland AL, Ghosh A, Tarran R.
Åstrand AB, et al. Among authors: hemmerling m.
Am J Physiol Lung Cell Mol Physiol. 2015 Jan 1;308(1):L22-32. doi: 10.1152/ajplung.00163.2014. Epub 2014 Oct 31.
Am J Physiol Lung Cell Mol Physiol. 2015.
PMID: 25361567
Free PMC article.
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New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition.
Giorgetti M, Klymiuk N, Bähr A, Hemmerling M, Jinton L, Tarran R, Malmgren A, Åstrand A, Hansson GC, Ermund A.
Giorgetti M, et al. Among authors: hemmerling m.
Eur J Pharmacol. 2021 Aug 5;904:174123. doi: 10.1016/j.ejphar.2021.174123. Epub 2021 May 8.
Eur J Pharmacol. 2021.
PMID: 33974881
Free PMC article.
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