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Year Number of Results
2012 2
2014 1
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2018 2
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2023 1
2024 4

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Targeting the NLRP3 inflammasome in inflammatory diseases.
Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E. Mangan MSJ, et al. Nat Rev Drug Discov. 2018 Aug;17(8):588-606. doi: 10.1038/nrd.2018.97. Epub 2018 Jul 20. Nat Rev Drug Discov. 2018. PMID: 30026524 Review.
Mitochondrial damage activates the NLRP10 inflammasome.
Próchnicki T, Vasconcelos MB, Robinson KS, Mangan MSJ, De Graaf D, Shkarina K, Lovotti M, Standke L, Kaiser R, Stahl R, Duthie FG, Rothe M, Antonova K, Jenster LM, Lau ZH, Rösing S, Mirza N, Gottschild C, Wachten D, Günther C, Kufer TA, Schmidt FI, Zhong FL, Latz E. Próchnicki T, et al. Among authors: mangan msj. Nat Immunol. 2023 Apr;24(4):595-603. doi: 10.1038/s41590-023-01451-y. Epub 2023 Mar 20. Nat Immunol. 2023. PMID: 36941400
Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Auger JP, Zimmermann M, Faas M, Stifel U, Chambers D, Krishnacoumar B, Taudte RV, Grund C, Erdmann G, Scholtysek C, Uderhardt S, Ben Brahim O, Pascual Maté M, Stoll C, Böttcher M, Palumbo-Zerr K, Mangan MSJ, Dzamukova M, Kieler M, Hofmann M, Blüml S, Schabbauer G, Mougiakakos D, Sonnewald U, Hartmann F, Simon D, Kleyer A, Grüneboom A, Finotto S, Latz E, Hofmann J, Schett G, Tuckermann J, Krönke G. Auger JP, et al. Among authors: mangan msj. Nature. 2024 May;629(8010):184-192. doi: 10.1038/s41586-024-07282-7. Epub 2024 Apr 10. Nature. 2024. PMID: 38600378
Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Lauterbach MA, Hanke JE, Serefidou M, Mangan MSJ, Kolbe CC, Hess T, Rothe M, Kaiser R, Hoss F, Gehlen J, Engels G, Kreutzenbeck M, Schmidt SV, Christ A, Imhof A, Hiller K, Latz E. Lauterbach MA, et al. Among authors: mangan msj. Immunity. 2019 Dec 17;51(6):997-1011.e7. doi: 10.1016/j.immuni.2019.11.009. Immunity. 2019. PMID: 31851905 Free article.
Targeting the NLRP3 inflammasome in inflammatory diseases.
Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E. Mangan MSJ, et al. Nat Rev Drug Discov. 2018 Sep;17(9):688. doi: 10.1038/nrd.2018.149. Epub 2018 Aug 17. Nat Rev Drug Discov. 2018. PMID: 30116046
16 results