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Mitochondrial damage activates the NLRP10 inflammasome.
Próchnicki T, Vasconcelos MB, Robinson KS, Mangan MSJ, De Graaf D, Shkarina K, Lovotti M, Standke L, Kaiser R, Stahl R, Duthie FG, Rothe M, Antonova K, Jenster LM, Lau ZH, Rösing S, Mirza N, Gottschild C, Wachten D, Günther C, Kufer TA, Schmidt FI, Zhong FL, Latz E. Próchnicki T, et al. Among authors: rosing s. Nat Immunol. 2023 Apr;24(4):595-603. doi: 10.1038/s41590-023-01451-y. Epub 2023 Mar 20. Nat Immunol. 2023. PMID: 36941400
Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release.
Rösing S, Ullrich F, Meisterfeld S, Schmidt F, Mlitzko L, Croon M, Nattrass RG, Eberl N, Mahlberg J, Schlee M, Wieland A, Simon P, Hilbig D, Reuner U, Rapp A, Bremser J, Mirtschink P, Drukewitz S, Zillinger T, Beissert S, Paeschke K, Hartmann G, Trifunovic A, Bartok E, Günther C. Rösing S, et al. Nat Commun. 2024 Feb 20;15(1):1534. doi: 10.1038/s41467-024-45535-1. Nat Commun. 2024. PMID: 38378748 Free PMC article.
Metabolic Syndrome in Psoriasis Is Associated With Upregulation of CXCL16 on Monocytes and a Dysbalance in Innate Lymphoid Cells.
Schielke L, Zimmermann N, Hobelsberger S, Steininger J, Strunk A, Blau K, Hernandez J, Künzel S, Ziegenbalg R, Rösing S, Beissert S, Abraham S, Günther C. Schielke L, et al. Among authors: rosing s. Front Immunol. 2022 Jun 17;13:916701. doi: 10.3389/fimmu.2022.916701. eCollection 2022. Front Immunol. 2022. PMID: 35784287 Free PMC article.