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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1938 1
1963 1
1968 1
1971 1
1973 1
1974 1
1975 38
1976 45
1977 65
1978 67
1979 72
1980 71
1981 84
1982 114
1983 128
1984 137
1985 130
1986 144
1987 169
1988 153
1989 156
1990 156
1991 174
1992 186
1993 181
1994 205
1995 202
1996 249
1997 255
1998 251
1999 280
2000 274
2001 299
2002 341
2003 347
2004 388
2005 454
2006 385
2007 430
2008 388
2009 416
2010 450
2011 525
2012 589
2013 639
2014 636
2015 647
2016 497
2017 393
2018 670
2019 635
2020 671
2021 698
2022 715
2023 621
2024 116

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14,538 results

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Page 1
Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy.
Luoma AM, Suo S, Williams HL, Sharova T, Sullivan K, Manos M, Bowling P, Hodi FS, Rahma O, Sullivan RJ, Boland GM, Nowak JA, Dougan SK, Dougan M, Yuan GC, Wucherpfennig KW. Luoma AM, et al. Among authors: sullivan rj, sullivan k. Cell. 2020 Aug 6;182(3):655-671.e22. doi: 10.1016/j.cell.2020.06.001. Epub 2020 Jun 29. Cell. 2020. PMID: 32603654 Free PMC article.
Here we report a comprehensive single-cell analysis of immune cell populations in colitis, a common and severe side effect of checkpoint blockade. We observed a striking accumulation of CD8 T cells with highly cytotoxic and proliferative states and no evidence of regulator …
Here we report a comprehensive single-cell analysis of immune cell populations in colitis, a common and severe side effect of checkpoint blo …
gammadelta T cells regulate the intestinal response to nutrient sensing.
Sullivan ZA, Khoury-Hanold W, Lim J, Smillie C, Biton M, Reis BS, Zwick RK, Pope SD, Israni-Winger K, Parsa R, Philip NH, Rashed S, Palm N, Wang A, Mucida D, Regev A, Medzhitov R. Sullivan ZA, et al. Science. 2021 Mar 19;371(6535):eaba8310. doi: 10.1126/science.aba8310. Science. 2021. PMID: 33737460
The "on-demand" induction of this machinery required gammadelta T cells, which regulated this program through the suppression of interleukin-22 production by type 3 innate lymphoid cells. ...Thus, this work identifies a role for gammadelta T cells in nutrient sensin …
The "on-demand" induction of this machinery required gammadelta T cells, which regulated this program through the suppression of inte …
Chromosome 22q11.2 deletion syndrome and DiGeorge syndrome.
Sullivan KE. Sullivan KE. Immunol Rev. 2019 Jan;287(1):186-201. doi: 10.1111/imr.12701. Immunol Rev. 2019. PMID: 30565249 Review.
Our work has shown that the primary effect of thymic hypoplasia is to restrict T cell production. Subsequent homeostatic proliferation and perhaps other factors drive a Th2 polarization, most obvious in adulthood. This contributes to atopic risk in this population. Thymic …
Our work has shown that the primary effect of thymic hypoplasia is to restrict T cell production. Subsequent homeostatic proliferatio …
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity.
Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, Anderson AC. Sakuishi K, et al. Among authors: sullivan jm. J Exp Med. 2010 Sep 27;207(10):2187-94. doi: 10.1084/jem.20100643. Epub 2010 Sep 6. J Exp Med. 2010. PMID: 20819927 Free PMC article.
PD-1 has been identified as a marker of exhausted T cells in chronic disease states, and blockade of PD-1-PD-1L interactions has been shown to partially restore T cell function. We have found that T cell immunoglobulin mucin (Tim) 3 is expressed on CD8(+) tum …
PD-1 has been identified as a marker of exhausted T cells in chronic disease states, and blockade of PD-1-PD-1L interactions has been …
Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases.
Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG. Sullivan KM, et al. Gut. 2023 Feb;72(2):325-337. doi: 10.1136/gutjnl-2021-325808. Epub 2022 Jun 15. Gut. 2023. PMID: 35705369 Free PMC article.
We sought to evaluate the effect of interleukin 10 (IL-10) blockade on endogenous T cell and chimeric antigen receptor T (CAR-T) cell antitumour function in CRLM slice cultures. ...In human CRLM slices, alphaIL-10 increased CEA-specific CAR-T cell acti …
We sought to evaluate the effect of interleukin 10 (IL-10) blockade on endogenous T cell and chimeric antigen receptor T (CAR- …
Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering.
Michels KR, Sheih A, Hernandez SA, Brandes AH, Parrilla D, Irwin B, Perez AM, Ting HA, Nicolai CJ, Gervascio T, Shin S, Pankau MD, Muhonen M, Freeman J, Gould S, Getto R, Larson RP, Ryu BY, Scharenberg AM, Sullivan AM, Green S. Michels KR, et al. Among authors: sullivan am. J Immunother Cancer. 2023 Mar;11(3):e006292. doi: 10.1136/jitc-2022-006292. J Immunother Cancer. 2023. PMID: 36918221 Free PMC article.
RESULTS: In vitro, administration of UB-VV100 resulted in dose-dependent and anti-CD3 scFv-dependent T-cell activation and CAR T-cell transduction. The resulting CAR T cells exhibited selective expansion in rapamycin and antigen-dependent activity against mal …
RESULTS: In vitro, administration of UB-VV100 resulted in dose-dependent and anti-CD3 scFv-dependent T-cell activation and CAR T …
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. Among authors: sullivan sa. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.
Stimulated CD4(+) T lymphocytes can differentiate into effector T cell (Teff) or inducible regulatory T cell (Treg) subsets with specific immunological roles. ...Importantly, AMP-activated protein kinase stimulation was sufficient to decrease Glut1 and increa …
Stimulated CD4(+) T lymphocytes can differentiate into effector T cell (Teff) or inducible regulatory T cell (Treg) sub …
Pathophysiology of immune thrombocytopenia.
Li J, Sullivan JA, Ni H. Li J, et al. Among authors: sullivan ja. Curr Opin Hematol. 2018 Sep;25(5):373-381. doi: 10.1097/MOH.0000000000000447. Curr Opin Hematol. 2018. PMID: 30015642 Review.
Recent findings suggest distinct heterogeneity in ITP including antibody-mediated platelet activation, Fc-independent desialylated platelet clearance, attenuation of platelet-mediated hepatic thrombopoietin generation, and decreased CD8 T-suppressor generation. These mecha …
Recent findings suggest distinct heterogeneity in ITP including antibody-mediated platelet activation, Fc-independent desialylated platelet …
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.
Tian M, Wei JS, Shivaprasad N, Highfill SL, Gryder BE, Milewski D, Brown GT, Moses L, Song H, Wu JT, Azorsa P, Kumar J, Schneider D, Chou HC, Song YK, Rahmy A, Masih KE, Kim YY, Belyea B, Linardic CM, Dropulic B, Sullivan PM, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL, Orentas RJ, Cheuk AT, Khan J. Tian M, et al. Among authors: sullivan pm. Cell Rep Med. 2023 Oct 17;4(10):101212. doi: 10.1016/j.xcrm.2023.101212. Epub 2023 Sep 28. Cell Rep Med. 2023. PMID: 37774704 Free PMC article.
In contrast, a panel of healthy human primary cells failed to activate 3A11 CAR T cells, confirming the selectivity of 3A11 CAR T cells against tumors with high FGFR4 expression. ...Therefore, our study credentials CAR T cell therapy targeting FGFR4 to treat …
In contrast, a panel of healthy human primary cells failed to activate 3A11 CAR T cells, confirming the selectivity of 3A11 CAR T …
Sex differences in T cells in hypertension.
Tipton AJ, Sullivan JC. Tipton AJ, et al. Among authors: sullivan jc. Clin Ther. 2014 Dec 1;36(12):1882-1900. doi: 10.1016/j.clinthera.2014.07.011. Epub 2014 Aug 16. Clin Ther. 2014. PMID: 25134971 Free PMC article. Review.
METHODS: A search of PubMed was conducted to determine the impact of sex on T cell-mediated control of BP. The search terms included sex, gender, estrogen, testosterone, inflammation, T cells, T regulatory cells, Th17 cells, hypertension, and blood pressure. …
METHODS: A search of PubMed was conducted to determine the impact of sex on T cell-mediated control of BP. The search terms included …
14,538 results
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