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Page 1
Late-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice.
bioRxiv [Preprint]. 2024 Jan 12:2024.01.12.575290. doi: 10.1101/2024.01.12.575290.
bioRxiv. 2024.
PMID: 38260683
Free PMC article.
Preprint.
Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity.
Heyden KE, Fiddler JL, Xiu Y, Malysheva OV, Handzlik MK, Phinney WN, Stiles L, Stabler SP, Metallo CM, Caudill MA, Field MS.
Heyden KE, et al.
PNAS Nexus. 2023 Mar 27;2(4):pgad105. doi: 10.1093/pnasnexus/pgad105. eCollection 2023 Apr.
PNAS Nexus. 2023.
PMID: 37077889
Free PMC article.
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Impairments in SHMT2 expression or cellular folate availability reduce oxidative phosphorylation and pyruvate kinase activity.
Fiddler JL, Blum JE, Heyden KE, Castillo LF, Thalacker-Mercer AE, Field MS.
Fiddler JL, et al. Among authors: heyden ke.
Genes Nutr. 2023 Mar 24;18(1):5. doi: 10.1186/s12263-023-00724-3.
Genes Nutr. 2023.
PMID: 36959541
Free PMC article.
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