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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 14
2003 27
2004 21
2005 19
2006 27
2007 35
2008 18
2009 27
2010 17
2011 24
2012 22
2013 31
2014 27
2015 21
2016 28
2017 32
2018 33
2019 25
2020 38
2021 31
2022 27
2023 31
2024 14

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513 results

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Page 1
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP. Matyskiela ME, et al. Among authors: handa h. Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22. Nature. 2016. PMID: 27338790
Molecular mechanisms of thalidomide and its derivatives.
Ito T, Handa H. Ito T, et al. Among authors: handa h. Proc Jpn Acad Ser B Phys Biol Sci. 2020;96(6):189-203. doi: 10.2183/pjab.96.016. Proc Jpn Acad Ser B Phys Biol Sci. 2020. PMID: 32522938 Free PMC article.
Molecular mechanisms of cereblon-based drugs.
Asatsuma-Okumura T, Ito T, Handa H. Asatsuma-Okumura T, et al. Among authors: handa h. Pharmacol Ther. 2019 Oct;202:132-139. doi: 10.1016/j.pharmthera.2019.06.004. Epub 2019 Jun 14. Pharmacol Ther. 2019. PMID: 31202702 Review.
Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4.
Kimura A, Takagi T, Thamamongood T, Sakamoto S, Ito T, Seki I, Okamoto M, Aono H, Serada S, Naka T, Imataka H, Miyake K, Ueda T, Miyanokoshi M, Wakasugi K, Iwamoto N, Ohmagari N, Iguchi T, Nitta T, Takayanagi H, Yamashita H, Kaneko H, Tsuchiya H, Fujio K, Handa H, Suzuki H. Kimura A, et al. Among authors: handa h. Ann Rheum Dis. 2023 Sep;82(9):1153-1161. doi: 10.1136/ard-2023-224055. Epub 2023 Jul 2. Ann Rheum Dis. 2023. PMID: 37400117
Postazacitidine clone size predicts long-term outcome of patients with myelodysplastic syndromes and related myeloid neoplasms.
Nannya Y, Tobiasson M, Sato S, Bernard E, Ohtake S, Takeda J, Creignou M, Zhao L, Kusakabe M, Shibata Y, Nakamura N, Watanabe M, Hiramoto N, Shiozawa Y, Shiraishi Y, Tanaka H, Yoshida K, Kakiuchi N, Makishima H, Nakagawa M, Usuki K, Watanabe M, Imada K, Handa H, Taguchi M, Kiguchi T, Ohyashiki K, Ishikawa T, Takaori-Kondo A, Tsurumi H, Kasahara S, Chiba S, Naoe T, Miyano S, Papaemanuil E, Miyazaki Y, Hellström-Lindberg E, Ogawa S. Nannya Y, et al. Among authors: handa h. Blood Adv. 2023 Jul 25;7(14):3624-3636. doi: 10.1182/bloodadvances.2022009564. Blood Adv. 2023. PMID: 36989067 Free PMC article.
[Cereblon as a primary target of IMiDs].
Ito T, Handa H. Ito T, et al. Among authors: handa h. Rinsho Ketsueki. 2019;60(9):1013-1019. doi: 10.11406/rinketsu.60.1013. Rinsho Ketsueki. 2019. PMID: 31597822 Review. Japanese.
Cystathionine β-synthase and PGRMC1 as CO sensors.
Kabe Y, Yamamoto T, Kajimura M, Sugiura Y, Koike I, Ohmura M, Nakamura T, Tokumoto Y, Tsugawa H, Handa H, Kobayashi T, Suematsu M. Kabe Y, et al. Among authors: handa h. Free Radic Biol Med. 2016 Oct;99:333-344. doi: 10.1016/j.freeradbiomed.2016.08.025. Epub 2016 Aug 24. Free Radic Biol Med. 2016. PMID: 27565814 Review.
[Multiple myeloma].
Handa H. Handa H. Rinsho Ketsueki. 2014 Feb;55(2):201-12. Rinsho Ketsueki. 2014. PMID: 24598188 Review. Japanese. No abstract available.
Teratogenic effects of thalidomide: molecular mechanisms.
Ito T, Ando H, Handa H. Ito T, et al. Among authors: handa h. Cell Mol Life Sci. 2011 May;68(9):1569-79. doi: 10.1007/s00018-010-0619-9. Epub 2011 Jan 5. Cell Mol Life Sci. 2011. PMID: 21207098 Free PMC article. Review.
513 results